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Sequence analysis of expressed proteins
1999Abstract The generation of recombinant proteins may be considered a relatively facile process nowadays. The wide range of expression systems available, and the marketing of specialized molecular biological kits by a number of manufacturers, virtually ensure that reasonable quantities of recombinant proteins can be produced in most ...
Jeff N Keen, Alison E Ashcroft
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The chemistry of protein sequence analysis
2000N-terminal sequence analysis by Edman chemistry continues to play an important role in the structural analysis of proteins and peptides. Improvements in the sensitivity of the method have been achieved mainly at the level of increasing the sensitivity of the on-line analysis of PTH amino acids by RP-HPLC (reverse phase high performance chromatography).
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Sequence analysis of membrane proteins
1986The primary structures of proteins can be determined by two distinct methods: directly by sequence analysis of the protein or indirectly by DNA sequence analysis of the corresponding gene or c-DNA. The direct protein sequence analysis methods are strongly influenced by the nature of the protein.
John E. Walker, Ian M. Fearnley
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Pitfalls of protein sequence analysis
Current Opinion in Biotechnology, 1996B, Rost, A, Valencia
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Spectral Analysis of Protein Sequences
2006Analysis of protein sequences can avoid many problems inherently existing in the study of nucleotide sequences given the knowledge that DNA sequences contain all the information for regulating protein expression. This paper presents a spectral approach for calculating the similarity of protein sequences, which can be useful for the inferences of ...
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Robust deep learning–based protein sequence design using ProteinMPNN
Science, 2022Justas Dauparas +2 more
exaly