Results 11 to 20 of about 6,859,921 (298)
Large scale hierarchical clustering of protein sequences [PDF]
BMC Bioinformatics, 2005 Background Searching a biological sequence database with a query sequence looking for homologues has become a routine operation in computational biology.
Stoye Jens, Krause Antje, Vingron Martin
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Peptide vocabulary analysis reveals ultra-conservation and homonymity in protein sequences [PDF]
, 2007 A new algorithm is presented for vocabulary analysis (word detection) in texts of human origin. It performs at 60%-70% overall accuracy and greater than 80% accuracy for longer words, and approximately 85% sensitivity on Alice in Wonderland, a ...
Gatherer, Derek
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Protein sequence databases [PDF]
Current Opinion in Chemical Biology, 2004 A variety of protein sequence databases exist, ranging from simple sequence repositories, which store data with little or no manual intervention in the creation of the records, to expertly curated universal databases that cover all species and in which the original sequence data are enhanced by the manual addition of further information in each ...
Apweiler, Rolf +2 more
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Protein Ladder Sequencing [PDF]
Science, 1993 A new approach to protein sequencing is described. It consists of two steps: (i) ladder-generating chemistry, the controlled generation from a polypeptide chain by wet chemistry of a family of sequence-defining peptide fragments, each differing from the next by one amino acid; and (ii) data readout, a one-step readout of the resulting protein ...
B T, Chait +3 more
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Swaps in protein sequences [PDF]
Proteins: Structure, Function, and Bioinformatics, 2002 AbstractAn important question in protein evolution is to what extent proteins may have undergone swaps (switches of domain or fragment order) during evolution. Such events might have occurred in several forms: Swaps of short fragments, swaps of structural and functional motifs, or recombination of domains in multidomain proteins.
Amit, Fliess, Benny, Motro, Ron, Unger
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Comparison of DNA Sequences with Protein Sequences
Genomics, 1997 The FASTA package of sequence comparison programs has been expanded to include FASTX and FASTY, which compare a DNA sequence to a protein sequence database, translating the DNA sequence in three frames and aligning the translated DNA sequence to each sequence in the protein database, allowing gaps and frameshifts.
W R, Pearson +3 more
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MisPred: a resource for identification of erroneous protein sequences in public databases [PDF]
, 2013 Correct prediction of the structure of protein-coding genes of higher eukaryotes is still a difficult task; therefore, public databases are heavily contaminated with mispredicted sequences.
Nagy, Alinda, Patthy, László
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Extended many-item similarity indices for sets of nucleotide and protein sequences
Computational and Structural Biotechnology Journal, 2021 Quantification of similarities between protein sequences or DNA/RNA strands is a (sub-)task that is ubiquitously present in bioinformatics workflows, and is usually accomplished by pairwise comparisons of sequences, utilizing simple (e.g.
Dávid Bajusz +3 more
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Navigating the amino acid sequence space between functional proteins using a deep learning framework [PDF]
PeerJ Computer Science, 2021 Motivation Shedding light on the relationships between protein sequences and functions is a challenging task with many implications in protein evolution, diseases understanding, and protein design. The protein sequence space mapping to specific functions
Tristan Bitard-Feildel
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Development and Validation of Optimization Methods for the Design of Protein Sequences and Combinatorial Libraries [PDF]
, 2009 To facilitate the design of protein sequences with desired properties, simulation techniques have been developed to allow large portions of amino acid sequence space to be evaluated by computer.
Allen, Benjamin Daniel
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