Results 181 to 190 of about 209,848 (307)

Serine/Threonine-Protein Kinase Nek9 [PDF]

, 2020
openaire   +1 more source

Parkinson's Disease Patient‐Specific Striatum Organoids Show Hallmarks of Increased Inflammation

Movement Disorders, EarlyView.
Abstract Background Dopaminergic neurons from the substantia nigra pars compacta project their axons into the dorsal striatum, forming the nigrostriatal pathway. In Parkinson's disease (PD), dopaminergic terminals degenerate in the striatum, leading to dopamine depletion, which in turn causes alterations in the basal ganglia circuits that are essential
Kyriaki Barmpa, Claudia Saraiva, Alise Zagare, Mona Tuzza, Joseph Longworth, Elisa Zuccoli, Katrin Hufnagel, Florian Skwirblies, Ronny Schmidt, Dirk Brenner, Christoph Schröder, Jens C. Schwamborn   +11 more
wiley   +1 more source

Insulin Signaling in Alzheimer's Disease: Association with Brain Insulin Resistance. [PDF]

Int J Mol Sci
Pliszka M, Szablewski L.
europepmc   +1 more source

Quantitative proteome and phosphoproteome analyses of streptomyces coelicolor reveal proteins and phosphoproteins modulating differentiation and secondary metabolism [PDF]

González Quiñonez, Nathaly del Valle, Gorshkov, V., Jensen, O. N., Kovalchuk, S., López García, María Teresa (Bio), Manteca Fernández, Ángel, Rioseras de Bustos, Beatriz, Rogowska Wrzesinska, A., Shliaha, P. V., Yagüe Menéndez, Paula   +9 more
core   +1 more source

Serine/Threonine-Protein Kinase MARK2 [PDF]

, 2020
openaire   +1 more source

CRISPR‐Cas9 Genome‐Wide Screening in Paediatric Cancer: Functional Genomics for Target Discovery and the Improvement of Existing Therapies

Medicinal Research Reviews, EarlyView.
ABSTRACT CRISPR‐Cas9 genome‐wide screening has been instrumental towards identifying novel targets for drug discovery in cancer research. However, much of this research has centred specifically on adult cancers, with paediatric cancers being underserviced by current research and screening.
Steven He, Patrick Connerty, Antoine de Weck   +2 more
wiley   +1 more source

Integrated Expression Analysis May Support Serine/Threonine Kinases as Common Hub Genes in Breast Cancer. [PDF]

Iran J Med Sci
Ekhtiyari MS, Ghaderi-Zefrehei M, Mogharari Z, Yousefi M, Bigdeli A, Nasre Esfahani E, Shahriarpour H, Leschm BJ.   +7 more
europepmc   +1 more source

Serine/Threonine-Protein Kinase DCLK1 [PDF]

, 2020
openaire   +1 more source

Multiple Roles of Protamine Kinase SRPK1 and Phosphatase PP1γ in Sperm Development

PROTEOMICS, EarlyView.
ABSTRACT Protein phosphorylation regulates key events of male germ cell differentiation. In the testis, SRPK1 and PP1γ are involved in protamine phosphorylation and dephosphorylation, respectively, and their deregulation is linked to defective chromatin structure and male infertility.
Alberto de la Iglesia, Mélina Blanco, Meritxell Jodar, Olivier Feudjio, Marjorie Leduc, Judit Castillo, Julie Cocquet, Rafael Oliva   +7 more
wiley   +1 more source

Modulation of host functions by bacterial serine/threonine protein kinase effector proteins. [PDF]

J Biol Chem
Ge J, Qiu J.
europepmc   +1 more source