Results 191 to 200 of about 142,067 (264)

An AI-Ready Phosphorylation Meta-Analysis for <i>Saccharomyces cerevisiae</i>. [PDF]

J Proteome Res
Boswell EL, Ramsbottom KA, Fan J, Perez-Riverol Y, Bowler-Barnett EH, Sun Z, Mesdaghi S, Rigden DJ, Martin MJ, Deutsch EW, Vizcaíno JA, Jones AR.   +11 more
europepmc   +1 more source

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

Integrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang, Yonggang Niu, Shengkang Men, Yanghuilin Zhang, Xiaolong Tang, Kenneth B. Storey, Qiang Chen   +6 more
wiley   +1 more source

Ole-4, a novel synthetic derivative of Oleuropein, enhances antitumor immunity and modulates kinase activity-dependent signaling. [PDF]

J Transl Med
Angelis NV, Paronis E, Sarikaki G, Nikolakopoulos KS, Velentzas AD, Mikropoulou EV, Stathopoulos P, Katsimpoulas M, Kostomitsopoulos NG, Aggeli IK, Papageorgis P, Kostopoulos IV, Efthimiopoulos S, Iliopoulos D, Baxevanis CN, Kostakis IK, Skaltsounis AL, Stravopodis DJ, Tsitsilonis OE.   +18 more
europepmc   +1 more source

Kaempferol Protects Intestinal Health in Chinese Forest Musk Deer Possibly by Regulating Intestinal Microbiota and Inhibiting the NF‐κB/NLRP3 Signaling Pathway

Integrative Zoology, EarlyView.
Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu, Zhanjun Ren, Xiuzhu Sun, Shuhui Wang   +3 more
wiley   +1 more source

Phenotypic transformation of HCC827 cells revealed by evaluation of human platelet lysate as a sustainable fetal bovine serum replacement. [PDF]

Front Cell Dev Biol
Woitaske-Proske C, Keller N, Zinke L, Schade D, Peifer C.   +4 more
europepmc   +1 more source

Gut Microbiota of Gray Snub‐Nosed Monkeys: Adaptation to Seasonal Variations Through Energy Compensation and Thermogenesis

Integrative Zoology, EarlyView.
Based on metagenome‐assembled genomes (MAGs), the gut microbiota of the gray snub‐nosed monkeys recovered 1229 non‐redundant MAGs. The gut microbiota showed an enhanced capacity to produce energy substrates with increased conversion activity of these substrates during winter.
Yue Sun, Mingyi Zhang, Xiaochen Wang, Xiaolong Huang, Yanze Yu, Huijuan Pan, Haibo Li, Lei Shi, Wei Yang, Chen Zhang, Bo Ding, Xun Liu, Jianfeng Li, Changjiang Qian, Boxing Cheng, Chao Zhang, Jingcheng Ran, Ming Li   +17 more
wiley   +1 more source

Decoding Cdk1 control: from mitotic thresholds to meiotic specificity. [PDF]

Chromosome Res
Touati SA.
europepmc   +1 more source

A Novel Antioxidant Peptide Cath‐Np Derived from Nanorana parkeri Attenuates UVB‐Induced Skin Photodamage in Mice

Integrative Zoology, EarlyView.
Schematic representation of Cath‐Np as an antioxidant suppressing acute skin damage caused by ultraviolet B (UVB) radiation in mice. Cath‐Np inhibits the activation of p53 and mitogen‐activated protein kinase pathways while it activates the Nrf2 pathway by its strong antioxidant effects, and accordingly suppresses the expression of inflammatory factors
Hang Liao, Xiaoxiao Shen, Jinwei Chai, Kai wang, Jiena Wu, Jianxi Yang, Ming Chen, Guoxiang Mo, Xueqing Xu   +8 more
wiley   +1 more source

STK17A (DRAK1) at the crossroads of apoptosis, immunity, and cancer: Emerging roles and therapeutic opportunities. [PDF]

Theranostics
Gonçalves LCP, Rastoin O, Morozova V, Buzet C, Bennetot A, Pagès G, Ronco C, Dufies M.   +7 more
europepmc   +1 more source

Basophils in Immunity: Activation Pathways, Roles in Allergy and AllergoOncology and Application of the Basophil Activation Test

Allergy, EarlyView.
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan, Sofia Vlasova, Alicia Chenoweth, Debra H. Josephs, Heather J. Bax, Sophia N. Karagiannis   +5 more
wiley   +1 more source