Results 211 to 220 of about 212,255 (348)

Alogliptin Reduces Oxidative Stress in Cardiomyocytes and Ameliorates Diabetic Cardiomyopathy via the AURKB/NLGN2 Signaling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cardiomyopathy (DCM) is a common complication of diabetes mellitus. This study investigated the effects of alogliptin on DCM and its underlying mechanisms. A DCM model was constructed and treated with alogliptin. Downstream targets of alogliptin were screened using bioinformatics analysis.
Li‐Jing Jiao, Jing Zhou, Jing Wang, Si‐Nan Zhao, Zhan‐Sheng Zhao, Qian Wang, Ya‐Nan Xie, Wei Jiao   +7 more
wiley   +1 more source

Estrogen Regulates Microtubule-Associated Protein 1 Light Chain 3 in Mouse Uterine Endometrial Epithelium. [PDF]

Dev Reprod
Moon S, Lee S, Choi Y.
europepmc   +1 more source

X-ray diffraction data for the crystal Structure of serine/threonine-protein kinase (AEK1) T376D, S395D Mutant from Trypanosoma brucei (AMP-PNP) (10JU)

Seattle Structural Genomics Center for Infectious Disease (SSGCID)
openalex   +1 more source

A Tightly Associated Serine/Threonine Protein Kinase Regulates Phosphoinositide 3-Kinase Activity

, 1993
Christopher L. Carpenter, Kurt R. Auger, Brian Duckworth, Weimin Hou, Brian Schaffhausen, Lewis C. Cantley   +5 more
openalex   +2 more sources

In Staphylococcus aureus the regulation of pyruvate kinase activity by serine/threonine protein kinase favors biofilm formation [PDF]

, 2014
D. Vasu, Manne Mudhu Sunitha, Lokanathan Srikanth, Vimjam Swarupa, Uppu Venkateswara Prasad, K. Sireesha, Sthanikam Yeswanth, P. Santhosh Kumar, K. Venkatesh, Abhijit Chaudhary, Potukuchi Venkata Gurunadha Krishna Sarma   +10 more
openalex   +1 more source

Serine/Threonine-Protein Kinase SMG1 [PDF]

, 2020
openaire   +1 more source

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

PHGDH phosphorylation mediated by WNK1 serves as a dual marker of metabolic vulnerability and responsiveness to oxaliplatin treatment. [PDF]

Proc Natl Acad Sci U S A
Fang S, Jin G, Yan M, Song Y, Zhao S, Zhang C, Shao Y, Zhao K, Liu M, Wang Z, Jia X, Guo Q, Guo M, Wang M, Guo Z, Dong Z.   +15 more
europepmc   +1 more source

LKB1 Loss Sensitizes Lung Tumor Spheres to Mitomet‐Induced Ferroptosis, and These Effects are Enhanced by mTOR Inhibition

Molecular Carcinogenesis, EarlyView.
ABSTRACT Owing to their robust antioxidant defense mechanisms, cancer stem‐like cells (CSCs) maintain a low level of oxidative stress, which is crucial for preserving stemness and pluripotency. Therefore, agents that either directly generate reactive oxygen species (ROS) or inhibit the antioxidant defense systems can selectively induce oxidative cell ...
Xueqing Liang, Ali Nakhi, Peter I. Dosa, Gunda I. Georg, Fekadu Kassie   +4 more
wiley   +1 more source

The Potential of the Inhibitors of the Transcriptional Enhanced Associate Domain Protein Factors (TEAD) as a Treatment for Cancer. [PDF]

ACS Med Chem Lett
Abdel-Magid AF.
europepmc   +1 more source