Results 211 to 220 of about 3,595,860 (302)
Phosphosite-specific co-regulation networks of MELK kinase: insights from integrative global phosphoproteomes. [PDF]
Khan NA +7 more
europepmc +1 more source
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan +5 more
wiley +1 more source
A conserved residue in the histidine kinase BceS tunes bacitracin stress responses in Bacillus subtilis. [PDF]
Gridley K, Koh A.
europepmc +1 more source
Lewy bodies are surrounded by granulovacuolar degeneration bodies in dementia with Lewy bodies
Here, we report Lewy bodies (LBs) to be enriched for tau‐laden granulovacuolar degeneration bodies (GVBs), suggesting a potential mechanistic interface between α‐synuclein and tau pathology in dementia with Lewy bodies (DLB). Abstract Lewy bodies (LBs), composed primarily of aggregated α‐synuclein (α‐syn), are the pathological hallmark of Lewy body ...
Searlait Thom +7 more
wiley +1 more source
DYRK kinases phosphorylate IL-17RA at S801. [PDF]
Moududee SA +4 more
europepmc +1 more source
Non‐canonical PKG1 regulation in cardiovascular health and disease
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley +1 more source
Structural insights into multitargeting <i>Mycobacterium tuberculosis</i> Pkn kinases. [PDF]
Pölläniemi A +6 more
europepmc +1 more source

