Results 241 to 250 of about 212,255 (348)

A tandem recruitment site in the pseudokinase scaffold PEAK3 is subject to phosphorylation-dependent regulation and cancer-associated mutations. [PDF]

J Biol Chem
Zhao T, Hou J, Hu C, Cotton TR, Daly RJ.
europepmc   +1 more source

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

The Journal of Pathology, EarlyView.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song, Yichen Liu, Chen Xu, Yaochen Zhang, Kaiming Xu, Dan Yao, Xiaoying Huang   +6 more
wiley   +1 more source

Can Fyn-Driven Wnt Activation Be the Key to Next-Generation Antifibrotic Therapy in CKD? [PDF]

Kidney360
Wang Y, Zhou D.
europepmc   +1 more source

Synthetic sulfoglycolipids targeting the serine–threonine protein kinase Akt

, 2016
Barbara Costa, Milind Shrinivas Dangate, M. Vetro, Giulia Donvito, Luca Gabrielli, Loredana Amigoni, Giuliana Cassinelli, Cinzia Lanzi, Michela Ceriani, Luca De Gioia, Giulia Filippi, Laura Cipolla, Nadia Zaffaroni, Paola Perego, Diego Colombo   +14 more
openalex   +1 more source

Serine/Threonine-Protein Kinase WNK1 [PDF]

, 2020
openaire   +1 more source

Genetic analysis of primary lung interdigitating dendritic cell sarcomas

The Journal of Pathology, EarlyView.
Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov, Juliana Faria Filipe, Sylvia Eidenhammer, German Ott, Iris Halbwedl, Karl Kashofer, Helmut Popper   +6 more
wiley   +1 more source

An update on regulation of the polymodal TRPV4 channel by protein phosphorylation. [PDF]

Channels (Austin)
Parthasarathy A, Zhang DX.
europepmc   +1 more source

LINC01012 Drives Hepatitis B‐Related Hepatocellular Carcinoma Progression Through HNRNPL‐Mediated Stabilization of Serine/Threonine‐Protein Kinase‐S

Jianhui Zhu, Peng Dai
openalex   +1 more source

Serine/Threonine-Protein Kinase Chk2 [PDF]

, 2020
openaire   +1 more source

Exploring the Reproductive Toxicity of Bisphenol S Through a Network Toxicology and Molecular Docking Analysis

Pediatric Discovery, EarlyView.
Utilizing network toxicology, molecular docking, and dynamic simulations to investigate the potential reproductive toxicity of bisphenol S (BPS). ABSTRACT The aim of this study was to investigate the potential reproductive toxicity of bisphenol S (BPS) and the related molecular mechanisms through a network toxicology approach.
Siyuan Wang, Yan Fu, Xu Huang, Qitong Guo, Xiangqin Zheng, Shengde Wu, Lianju Shen, Guanghui Wei   +7 more
wiley   +1 more source