Results 181 to 190 of about 3,595,860 (302)
Phytotherapy Research, EarlyView.ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley +1 more source
New Roles of Chk1 in Spindle Formation and Genome Integrity. [PDF]
Biology (Basel)Balafouti S, Zachos G, Petsalaki E.
europepmc +1 more source
Phytotherapy Research, EarlyView.This review summarizes how natural products, mainly including flavonoids, terpenoids, alkaloids, and polyphenols alleviate RA via PI3K/Akt pathway, regulating inflammation, proliferation, apoptosis, angiogenesis, and osteoclast differentiation. The figure was created by Figdraw (https://www.figdraw.com/#/).
Haishuo Ren +10 more
wiley +1 more source
Integrative phosphoproteomic analysis identifies functional roles of TRPM7 phosphosites in oncogenesis. [PDF]
Front BioinformPalollathil A +5 more
europepmc +1 more source
Molecular glues: Recent advances in cereblon substrate identification and mechanistic insights
Smart Molecules, EarlyView.Molecular glues exert diverse core biological functions by inducing or stabilizing protein–protein interactions, extending far beyond the traditional scope of targeted protein degradation. Key breakthroughs include expanded cereblon substrate recognition, sustained G protein‐coupled receptor megacomplex signaling, and the first orthosteric molecular ...
Qingyun Guan +5 more
wiley +1 more source