Results 261 to 270 of about 209,848 (307)

Circulating Rhythmic Metabolites and Causal Risk of Type 2 Diabetes in Adults in the Canadian Longitudinal Study on Aging

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Circadian regulation of metabolism is an important factor in metabolic health, yet the role of rhythmic metabolites in Type 2 diabetes development remains poorly understood. This study investigated associations between circulating rhythmic metabolites and incident Type 2 diabetes risk and evaluated causal relationships using two‐sample ...
Divya Joshi, Talha Rafiq, Marie Pigeyre, Renee de Mutsert, Femke Rutters, David J.T. Campbell, Jean‐Pierre Despres, Andre C. Carpentier, Joris Hoeks, Patrick Schrauwen, Parminder Raina   +10 more
wiley   +1 more source

Phosphoproteomic profiling of lipopolysaccharide stimulated toll-like receptor pathways in macrophages. [PDF]

Sci Data
Kim D, Yoon SH, Manes NP, Nita-Lazar A.
europepmc   +1 more source

Dynamics of the CD9 interactome during bacterial infection of epithelial cells by proximity labelling proteomics

The FEBS Journal, EarlyView.
We describe the CD9 interactome in epithelial cells for the first time. The interactome is diverse and dynamic and changes dependent on infection with specific bacteria. We validate these data by showing functional interaction between CD9 with CD44 or CD147. We therefore demonstrate that CD9 is a universal organiser of bacterial adhesion platforms able
Paige A. Wolverson, Isabel Fernandes Parreira, Ruth H. Thompson, Mark O. Collins, Jonathan G. Shaw, Luke R. Green   +5 more
wiley   +1 more source

Transcriptomics driven identification of hub gene miRNA interactions for biomarker and therapeutic target discovery in gynecological cancers. [PDF]

Front Oncol
Zhu Y, Chen S, Cao M, Liu W, Huang H, Huang K, Shi L.   +6 more
europepmc   +1 more source

Regulatory networks of FUR and NtcA are intertwined by transcriptional regulators, two-component systems, serine/threonine kinases, and sigma factors in <i>Anabaena</i> sp. PCC 7120. [PDF]

mSystems
Guío J, Peleato ML, Fillat MF, Sevilla E.   +3 more
europepmc   +1 more source

Discovery of the MELK-Nucleostemin Axis in Glioblastoma: Implications for p53 Regulation and Tumor Progression. [PDF]

J Microbiol Biotechnol
Baek S, Jeon H, Moon JS, Kim YE, Kang D, Kim S, Kim KR, Heo KS.   +7 more
europepmc   +1 more source

Serine/threonine protein kinase phosphorylation of DosR alters target gene transcription mechanics and regulates Mycobacterium tuberculosis response to nitric oxide stress. [PDF]

PLoS Genet
Sontag NR, Ruiz Manzano A, Ecker AMV, Galburt EA, Tan S.   +4 more
europepmc   +1 more source

Critical role of the CMGC insert sequence for tyrosine autophosphorylation in the protein kinase DYRK1B. [PDF]

Sci Rep
Detro-Dassen S, Schwandt K, Helmich P, Düsterhöft S, Becker W.   +4 more
europepmc   +1 more source