Results 281 to 290 of about 212,467 (329)

PROTEIN SERINE/THREONINE KINASES

Annual Review of Biochemistry, 1987
PERSPEC TIVES AND S UMMARy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 568 CYCLIC A MP -D EP END EN T PROTEIN KINASES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 568 CYCLIC G MP -D EPENDENT PROTEIN KINASE. . . . . . . . . . . . . . . .
Arthur M. Edelman, Donald K. Blumenthal, Edwin G. Krebs   +2 more
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Serine/threonine protein kinases in Drosophila

Trends in Genetics, 1990
The study of serine/threonine kinases in Drosophila is coming of age. Recently several kinases have been identified and their role in cell determination has been established. This review discusses these recent findings and describes the potential for genetic analyses of kinase activity and signal transduction.
Linda Ambrosio, Norbert Perrimon, Esther Siegfried   +2 more
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Serine/Threonine Protein Kinases and Apoptosis

Experimental Cell Research, 2000
Over the past decade, our understanding of apoptosis, or programmed cell death, has increased greatly, with the identification of some of the major components of the apoptotic programme and the processes regulating their activation. Although apoptosis is an intrinsic process present in all cells, it can be regulated by extrinsic factors, including ...
Janet M. Lord, Elizabeth M. Deacon, Dagmar Scheel-Toellner, Mike Salmon, Nick V. Henriquez, Timothy Cross   +5 more
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Recent advances in bacterial signaling by serine/threonine protein kinases

Trends in Microbiology, 2022
It has been nearly three decades since the discovery of the first bacterial serine/threonine protein kinase (STPK). Since then, a blend of technological advances has led to the characterization of a multitude of STPKs and phosphorylation substrates in several bacterial species that finely regulate intricate signaling cascades. Years of intense research
Sathya Narayanan Nagarajan, Cassandra Lenoir, Christophe Grangeasse   +2 more
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Serine/Threonine Protein Kinases and Phosphatases in Filamentious Fungi

Fungal Genetics and Biology, 1999
Protein phosphorylation and dephosphorylation are one of the central currencies by which living cells perceive and respond to environmental cues. A number of fundamental processes in fungi such as the cell cycle, transcription, and mating have been shown to require protein phosphorylation. The analysis of protein kinases and phosphatases in filamentous
Oded Yarden, Martin B. Dickman
openaire   +3 more sources

Serine threonine protein kinases of mycobacterial genus: phylogeny to function [PDF]

Physiological Genomics, 2007
Serine/threonine protein kinases (STPKs) are known to act as sensors of environmental signals that thereby regulate developmental changes and host pathogen interactions. In this study, we carried out comparative genome analysis of six completely sequenced pathogenic and nonpathogenic mycobacterial species to systematically characterize the STPK ...
Anil K. Tyagi, Yogendra Singh, Azeet Narayan, Adesh K. Saini, Preeti Sachdeva, Kirti Sharma   +5 more
openaire   +2 more sources

Protein Serine/Threonine Kinases

2000
The reversible phosphorylation of proteins by protein kinases is the most extensively used molecular mechanism regulating cellular functions in eukaryotes. Essentially all major cellular processes, including cell growth and differentiation, motility, metabolism, and communication between cells, are in some way regulated by protein phosphorylation (Fig.
Heierhorst, Jorg, Pearson, Richard, Horne, James, Bozinovski, Steven, Kobe, Bostjan, Kemp, Bruce E.   +5 more
openaire   +3 more sources

Identification and characterization of the serine/threonine protein kinases in Bifidobacterium

Archives of Microbiology, 2014
Six genes encoding the bifidobacterial Hanks-type (eukaryote-like) serine/threonine protein kinases (STPK) were identified and classified. The genome of each bifidobacterial strain contains four conserved genes and one species-specific gene. Bifidobacterium longum and Bifidobacterium bifidum possess the unique gene found only in these species. The STPK
Natalia V. Zakharevich, M. G. Alekseeva, Olga V. Averina, Valery N. Danilenko, D. A. Mavletova, V. Z. Nezametdinova   +5 more
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Synthetic sulfoglycolipids targeting the serine–threonine protein kinase Akt

Bioorganic & Medicinal Chemistry, 2016
The serine-threonine protein kinase Akt, also known as protein kinase B, is a key component of the phosphoinositide 3-kinase (PI3K)-Akt-mTOR axis. Deregulated activation of this pathway is frequent in human tumors and Akt-dependent signaling appears to be critical in cell survival.
COSTA, BARBARA SIMONA, DANGATE, MILIND, Vetro, M, DONVITO, GIULIA, GABRIELLI, LUCA, AMIGONI, LOREDANA, Cassinelli, G, Lanzi, C, CERIANI, MICHELA, DE GIOIA, LUCA, FILIPPI, GIULIA, CIPOLLA, LAURA FRANCESCA, Zaffaroni, N, Perego, P, Colombo, D.   +14 more
openaire   +5 more sources

Protein-serine/threonine/tyrosine kinases in bacterial signaling and regulation

FEMS Microbiology Letters, 2013
In this review, we address some recent developments in the field of bacterial protein phosphorylation, focusing specifically on serine/threonine and tyrosine kinases. We present an overview of recent studies outlining the scope of physiological processes that are regulated by phosphorylation, ranging from cell cycle, growth, cell morphology, to ...
Ivan Mijakovic, Ivan Mijakovic, Ivan Mijakovic, Charlotte Cousin, Lei Shi, Yves Pagot, Yves Pagot, Sandrine Poncet, Abderahmane Derouiche   +8 more
openaire   +6 more sources