Results 261 to 270 of about 212,255 (348)
VIEW, EarlyView.Hepatocellular carcinoma (HCC) is frequently resistant to targeted therapies. We identify protein phosphatase Mg2+/Mn2+‐dependent 1G (PPM1G) as a key phosphatase that stabilizes mesenchymal‐epithelial transition factor (MET) by inhibiting its ubiquitination, thereby sustaining protein kinase B (AKT) signaling and promoting Twist‐mediated epithelial ...
Weixun Wu +8 more
wiley +1 more source
Insulin Signaling in Alzheimer's Disease: Association with Brain Insulin Resistance. [PDF]
Int J Mol SciPliszka M, Szablewski L.
europepmc +1 more source
Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang +3 more
wiley +1 more source
Modulation of host functions by bacterial serine/threonine protein kinase effector proteins. [PDF]
J Biol ChemGe J, Qiu J.
europepmc +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objective Currently, there are no blood biomarkers available for the early diagnosis of laryngeal squamous cell carcinoma (LSCC). The objective of this study was to search for potential plasma biomarkers for the diagnosis of LSCC. Methods Plasma samples were taken from patients with LSCC and healthy controls for proteomic analysis.
Shuang Teng +13 more
wiley +1 more source
Sperm capacitation in bulls, rams, bucks, and boars: molecular mechanisms and species-specific differences. [PDF]
Front Vet SciKaya A +4 more
europepmc +1 more source