Results 71 to 80 of about 148,098 (212)

LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells [PDF]

, 2010
The serine/threonine kinase LKB1 has a conserved role in Drosophila and nematodes to co-ordinate cell metabolism. During T lymphocyte development in the thymus, progenitors need to synchronize increased metabolism with the onset of proliferation and ...
Finlay, David, Doreen Cantrell, Macintyre, Andrew, Carmen Feijoo-carnero, Clarke, Rosemary, David Finlay, Alan Ashworth, Feijoo-Carnero, Carmen, Cantrell, Doreen, Tamas, Peter, Rosemary Clarke, Andrew Macintyre, Ashworth, Alan   +12 more
core   +1 more source

Mechanism of regulation of Raf-1 by Ca2+/Calmodulin-dependent kinase II

, 2011
The calcium-calmodulin dependent kinase II (CaMKII) is an ubiquitous serine/threonine protein kinase involved in multiple signalings and biological functions.
Salzano, Marcella
core  

The SNF1-type serine-threonine protein kinase SAPK4 regulates stress-responsive gene expression in rice

, 2008
Diedhiou CJ, Popova OV, Dietz K-J, Golldack D. The SNF1-type serine-threonine protein kinase SAPK4 regulates stress-responsive gene expression in rice. BMC PLANT BIOLOGY.
Popova Olga V, Dietz, Karl-Josef, Diédhiou Calliste J, Golldack Dortje, Golldack, Dortje, Dietz Karl-Josef, Diedhiou, Calliste J., Popova, Olga V.   +7 more
core   +1 more source

Serine-threonine protein kinase activities under colitis-associated carcinogenesis development

Current Issues in Pharmacy and Medical Sciences, 2010
Kinases are enzymes involved in mechanisms of ion transport, proliferation and differentiation control by phosphorylation of different protein substrates.
Lyudmila Ostapchenko, Olesya Drobinska, Olga Kravchenko   +2 more
doaj  

Genome-wide evolutionary analysis of TKL_CTR1-DRK-2 gene family and functional characterization reveals that TaCTR1 positively regulates flowering time in wheat

BMC Genomics
Background Flowering time has an important effect on regional adaptation and yields for crops. The tyrosine kinase-like (TKL) gene family is widely existed and participates in many biological processes in plants.
Peisen S. Su, Jingyu Li, Dongtian Zang, Zhiyu Wang, Yangyang Wu, Shatong Chi, Fanting Sun, Yufei Niu, Xuewen Hua, Jun Yan, Wenyang Ge   +10 more
doaj   +1 more source

Uncovering human kinase substrates in nipah proteome

Frontiers in Bioinformatics
Nipah virus (NiV) is a zoonotic pathogen that causes recurrent outbreaks with considerable implications for public health. Viruses engage host kinases to phosphorylate viral proteins, aiding replication and host disruption.
Vineetha Shaji, Vineetha Shaji, Akash Anil, Ayisha A. Jabbar, Althaf Mahin, Althaf Mahin, Ahmad Rafi, Amjesh Revikumar, Sowmya Soman, Ganesh Prasad, Sneha M. Pinto, Yashwanth Subbannayya, Yashwanth Subbannayya, Abhithaj Jayanandan, Rajesh Raju   +14 more
doaj   +1 more source

The 14-3-3 Protein Family, Beyond the Kinases and Phosphatases

Kinases and Phosphatases
Eukaryotic phosphorylation of serine and threonine residues is a central regulatory mechanism in cell signalling, carried out by more than 500 kinases and a diverse array of phosphatases.
Exequiel E. Barrera, Marina Uhart, Diego M. Bustos   +2 more
doaj   +1 more source

Regulation der humanen Aurora-A Kinase und Identifikation potentieller Interaktionspartner [PDF]

, 2004
The error-free segregation of duplicated chromosomes during cell division is essential for the maintenance of an intact genome. This process is brought about by a highly dynamic bipolar array of microtubules, the mitotic spindle.
Kufer, Thomas
core  

The coordination of T-cell function by serine/threonine kinases

, 2010
The function of T-lymphocytes during adaptive immune responses is directed by antigen receptors, costimulatory molecules, and cytokines. These extrinsic stimuli are coupled to a network of serine/threonine kinases that control the epigenetic ...
Cantrell, Doreen, Finlay, David, D. Finlay, D. Cantrell   +3 more
core   +1 more source

Deep evolutionary conservation of an intramolecular protein kinase activation mechanism [PDF]

, 2012
DYRK-family kinases employ an intramolecular mechanism to autophosphorylate a critical tyrosine residue in the activation loop. Once phosphorylated, DYRKs lose tyrosine kinase activity and function as serine/threonine kinases.
Cleghon Vaughn, Aman Singh (191216), Cleghon, V., Nathan Luebbering (191210), Sibbet Gary, Jingfen Han, Luebbering Nathan, Nathan Luebbering, Michael A J Ferguson, Singh, A., Aman Singh, Ferguson, M.A.J., Ferguson Michael A. J., Hong, W., Diego Miranda-Saavedra (36622), Michael A. J. Ferguson (166662), Jingfen Han, Han, J., Gary Sibbet (191221), Vaughn Cleghon (191224), Miranda-Saavedra Diego, Sibbet, G., Ferguson, M.A.J.; id_orcid, Han Jingfen, Miranda-Saavedra, D., Gary Sibbet, Luebbering, N., Diego Miranda-Saavedra, Michael A. J. Ferguson, Vaughn Cleghon, Singh Aman, Jingfen Han (191204)   +31 more
core   +1 more source