Results 21 to 30 of about 220,067 (314)

Sortase A substrate specificity in GBS pilus 2a cell wall anchoring. [PDF]

PLoS ONE, 2011
Streptococcus agalactiae, also referred to as Group B Streptococcus (GBS), is one of the most common causes of life-threatening bacterial infections in infants.
Francesca Necchi, Vincenzo Nardi-Dei, Massimiliano Biagini, Michael Assfalg, Annalisa Nuccitelli, Roberta Cozzi, Nathalie Norais, John L Telford, C Daniela Rinaudo, Guido Grandi, Domenico Maione   +10 more
doaj   +1 more source

Exopolysaccharide-associated protein sorting in environmental organisms: the PEP-CTERM/EpsH system. Application of a novel phylogenetic profiling heuristic

BMC Biology, 2006
Background Protein translocation to the proper cellular destination may be guided by various classes of sorting signals recognizable in the primary sequence. Detection in some genomes, but not others, may reveal sorting system components by comparison of
Ward Naomi, Paulsen Ian T, Haft Daniel H, Selengut Jeremy D   +3 more
doaj   +1 more source

Where do protein bodies of cereal seeds come from?

Frontiers in Plant Science, 2016
Protein bodies of cereal seeds consist of ordered, largely insoluble heteropolymers formed by prolamin storage proteins within the endoplasmic reticulum of developing endosperm cells.
Emanuela Pedrazzini, Davide Mainieri, Claudia Adriana Marrano, Alessandro Vitale   +3 more
doaj   +1 more source

Proteomic analysis identifies novel binding partners of BAP1.

PLoS ONE, 2021
BRCA1-associated protein 1 (BAP1) is a tumor suppressor and its loss can result in mesothelioma, uveal and cutaneous melanoma, clear cell renal cell carcinoma and bladder cancer. BAP1 is a deubiquitinating enzyme of the UCH class that has been implicated
Roy Baas, Fenna J van der Wal, Onno B Bleijerveld, Haico van Attikum, Titia K Sixma   +4 more
doaj   +1 more source

Vacuolar Sorting Receptor-Mediated Trafficking of Soluble Vacuolar Proteins in Plant Cells

Plants, 2014
Vacuoles are one of the most prominent organelles in plant cells, and they play various important roles, such as degradation of waste materials, storage of ions and metabolites, and maintaining turgor.
Hyangju Kang, Inhwan Hwang
doaj   +1 more source

Interplay of substrate retention and export signals in endoplasmic reticulum quality control. [PDF]

PLoS ONE, 2010
BACKGROUND: Endoplasmic reticulum (ER) quality control mechanisms are part of a comprehensive system to manage cell stress. The flux of molecules is monitored to retain folding intermediates and target misfolded molecules to ER-associated degradation ...
Shinichi Kawaguchi, Chia-Ling Hsu, Davis T W Ng   +2 more
doaj   +1 more source

Deep Cytometry: Deep learning with Real-time Inference in Cell Sorting and Flow Cytometry [PDF]

, 2019
Deep learning has achieved spectacular performance in image and speech recognition and synthesis. It outperforms other machine learning algorithms in problems where large amounts of data are available.
Chen, Claire Lifan, Jalali, Bahram, Li, Yueqin, Mahjoubfar, Ata, Niazi, Kayvan Reza, Pei, Li   +5 more
core   +2 more sources

Regulation of Notch Endosomal Sorting and Signaling by Drosophila Nedd4 Family Proteins [PDF]

Current Biology, 2004
The Notch receptor mediates a short-range signal that regulates many cell fate decisions. The misregulation of Notch has been linked to cancer and to developmental disorders. Upon binding to its ligands, Delta (Dl) or Serrate (Ser), the Notch ectodomain is shed by the action of an ADAM protease.
Wilkin, M B, Carbery, A M, Fostier, M, Aslam, H, Mazaleyrat, S L, Higgs, J, Myat, A, Evans, D A P, Cornell, M, Baron, M   +9 more
openaire   +4 more sources

Protein trafficking through the endosomal system prepares intracellular parasites for a home invasion [PDF]

, 2013
Toxoplasma (toxoplasmosis) and Plasmodium (malaria) use unique secretory organelles for migration, cell invasion, manipulation of host cell functions, and cell egress. In particular, the apical secretory micronemes and rhoptries of apicomplexan parasites
A Fomovska, AE Topolska, B Lige, B Shen, BF Kafsack, BJ Luft, C Lord, CA Hunter, Chetan E. Chitnis, Christian Slomianny, CY He, D Richard, DL Alexander, F Parussini, H El Hajj, HC Hoppe, HC Hoppe, I Mellman, J Schrevel, JB Dacks, JC Boothroyd, JE Rothman, JF Dubremetz, JM Harper, K Kremer, K Miranda, KA Joiner, KA Joiner, KM Hager, L Pelletier, L Sheiner, LH Bannister, LH Bannister, LM Kats, M Elias, M Tufet-Bayona, M Yang, Markus Meissner, ME Francia, MH Ngo, MH Ngo, MK Shaw, MS Breinich, MS Marks, NA Counihan, PJ Bradley, PJ Sloves, S Mogelsvang, SD Brydges, Stanislas Tomavo, VB Carruthers, Vern B. Carruthers, WM Henne, X Que, Z Dou   +54 more
core   +2 more sources

Characterization of Sorting Signals in the β-Amyloid Precursor Protein Cytoplasmic Domain [PDF]

Journal of Biological Chemistry, 1995
The beta-amyloid precursor protein (APP) is proteolytically processed to generate beta-amyloid protein, the principal protein component of neuropathological lesions characteristic of Alzheimer's disease. To investigate potential sorting signals in the cytoplasmic tail of APP, we transplanted APP cytoplasmic tail sequences into the cytoplasmic tail of ...
A, Lai, S S, Sisodia, I S, Trowbridge
openaire   +2 more sources