Results 201 to 210 of about 1,114,559 (262)

OrgNet: orientation-gnostic protein stability assessment using convolutional neural networks. [PDF]

Bioinformatics
Buyanov I, Sarycheva A, Popov P.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

CUL3^LRB E3 ubiquitin ligases control thermosensory growth in <i>Arabidopsis</i> by differentially regulating HY5 and PIF4 protein stability. [PDF]

Sci Adv
Singhal C, Upadhyaya G, Rajkumar MS, Modak A, Sethi V, Singh S, Das D, Jain M, Gangappa SN.   +8 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

The effect of low-voltage electrostatic field combined with <i>Allium mongolicum regel</i> on the quality and protein stability of frozen sheep liver. [PDF]

Food Chem X
Li J, Ma S, Bai J, Dong T, Yun X.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Improved Pendant-Bearing Glucose-Neopentyl Glycols for Membrane Protein Stability. [PDF]

Bioconjug Chem
Youn T, Kim G, Hariharan P, Li X, Ahmed W, Byrne B, Liu X, Guan L, Chae PS.   +8 more
europepmc   +1 more source

TRIM31 triggers colorectal carcinogenesis and progression by maintaining YBX1 protein stability through ubiquitination modification. [PDF]

Cell Death Dis
Li X, Wu Y, Guo J, Huang P, Li Q, Gao Z, Hu Y, Gao A, Sun M, Min H, Zhou J.   +10 more
europepmc   +1 more source

Mechanistic Insights into Cytokinin-Regulated Leaf Senescence in Barley: Genotype-Specific Responses in Physiology and Protein Stability. [PDF]

Int J Mol Sci
Skowron E, Trojak M, Szymkiewicz J, Nawrot D.   +3 more
europepmc   +1 more source

Root-Derived <i>Flammulina velutipes</i> Polysaccharides Improve Myofibrillar Protein Stability and Maintain <i>Catfish</i> Surimi Quality During Freeze-Thaw Cycling. [PDF]

Gels
Chen R, He N, Li X, Zhan Y, Zhang X, Zhu Y.   +5 more
europepmc   +1 more source