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PSSP-MFFNet: A Multifeature Fusion Network for Protein Secondary Structure Prediction

ACS Omega
Yifu Chen, Guanxing Chen, Calvin Yu-Chian Chen   +2 more
doaj   +1 more source

Functional and Structure Prediction of Hypothetical Proteins From <i>Listeria aquatica</i> FSL S10-1188: Bioinformatics Approaches. [PDF]

Biomed Res Int
Abdallah MM, Suliman RAI, Ahmed YT, Yahia M.   +3 more
europepmc   +1 more source

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Protein secondary structure prediction

Current Opinion in Structural Biology, 1995
The past year has seen a consolidation of protein secondary structure prediction methods. The advantages of prediction from an aligned family of proteins have been highlighted by several accurate predictions made 'blind', before any X-ray or NMR structure was known for the family.
S R, Krystek, W J, Metzler, J, Novotny
openaire   +5 more sources

Secondary Structure and Protein Deamidation

Journal of Pharmaceutical Sciences, 1999
The deamidation reactions of asparagine residues in alpha-helical and beta-turn secondary structural environments of peptides and proteins are reviewed. Both kinds of secondary structure tend to stabilize asparagine residues against deamidation, although the effects are not large.
M, Xie, R L, Schowen
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Protein Secondary Structure Prediction

2009
While the prediction of a native protein structure from sequence continues to remain a challenging problem, over the past decades computational methods have become quite successful in exploiting the mechanisms behind secondary structure formation. The great effort expended in this area has resulted in the development of a vast number of secondary ...
Pirovano, W.A., Heringa, J.
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Protein Secondary Structure Prediction with SPARROW

Journal of Chemical Information and Modeling, 2012
A first step toward predicting the structure of a protein is to determine its secondary structure. The secondary structure information is generally used as starting point to solve protein crystal structures. In the present study, a machine learning approach based on a complete set of two-class scoring functions was used.
Francesco, Bettella, Dawid, Rasinski, Ernst Walter, Knapp   +2 more
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Knowledge‐based protein secondary structure assignment

Proteins: Structure, Function, and Bioinformatics, 1995
AbstractWe have developed an automatic algorithm STRIDE for protein secondary structure assignment from atomic coordinates based on the combined use of hydrogen bond energy and statistically derived backbone torsional angle information. Parameters of the pattern recognition procedure were optimized using designations provided by the crystallographers ...
D, Frishman, P, Argos
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Chemogenomics with Protein Secondary-Structure Mimetics

2009
During molecular recognition of proteins in biological systems, helices, reverse turns, and beta-sheets are dominant motifs. Often there are therapeutic reasons for blocking such recognition sites, and significant progress has been made by medicinal chemists in the design and synthesis of semirigid molecular scaffolds on which to display amino acid ...
Garland R, Marshall, Daniel J, Kuster, Ye, Che   +2 more
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Protein Secondary Structure

2010
There are several methods available that can be used to gain information on secondary structure, apart from X-ray crystallography, which remains the ‘gold standard’.
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