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Protein secondary structure prediction

Current Opinion in Structural Biology, 1995
The past year has seen a consolidation of protein secondary structure prediction methods. The advantages of prediction from an aligned family of proteins have been highlighted by several accurate predictions made 'blind', before any X-ray or NMR structure was known for the family.
Jiri Novotny   +2 more
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Secondary Structure and Protein Deamidation

Journal of Pharmaceutical Sciences, 1999
The deamidation reactions of asparagine residues in alpha-helical and beta-turn secondary structural environments of peptides and proteins are reviewed. Both kinds of secondary structure tend to stabilize asparagine residues against deamidation, although the effects are not large.
Minli Xie, Richard L. Schowen
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Comparison of Super-secondary Structures in Proteins

Journal of Molecular Biology, 1973
Abstract A method of comparing the conformations of different, but structurally related proteins is described. Local variations, such as the systematic translation of a helix, or the position of deletions and insertions can be detected, and the correspondence of only marginally similar structures can be measured.
Michael G. Rossmann, S.T. Rao
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The role of secondary structure in protein structure selection

The European Physical Journal E, 2010
The presence of highly regular secondary structure motifs in protein structure is a fascinating area of study. The secondary structures play important roles in protein structure and protein folding. We investigate the folding properties of protein by introducing the effect of secondary structure elements. We observed the emergence of several structures
Yong-Yun Ji, You-Quan Li
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Protein Secondary Structure Prediction

2009
While the prediction of a native protein structure from sequence continues to remain a challenging problem, over the past decades computational methods have become quite successful in exploiting the mechanisms behind secondary structure formation. The great effort expended in this area has resulted in the development of a vast number of secondary ...
Jaap Heringa, Walter Pirovano
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Characterization of protein secondary structure

IEEE Signal Processing Magazine, 2004
What do proteins look like? Proteins are composed of fundamental building blocks of chemical molecules called amino acids. When a protein is synthesized by the cells, initially it is just a string of amino acids. This string arranges itself in a process called protein folding into a complex three-dimensional structure capable of exerting the function ...
Judith Klein-Seetharaman   +3 more
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Predicting secondary structures of proteins

IEEE Engineering in Medicine and Biology Magazine, 2005
The article presents the application of a new machine-learning algorithm for the prediction of secondary structures of proteins. The logical analysis of data (LAD) algorithm was applied to recognize which amino acids properties could be analyzed to deliver additional information, independent from protein homology, useful in determining the secondary ...
Piotr Lukasiak   +2 more
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Evaluation of secondary structure predictions in proteins

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1977
Data of 33 proteins are used to compare four methods which predict secondary structure from the amino acid sequence. The prediction of alpha-helices according to the histogram method of Argos et al. (Argos, P., Schwarz, J. and Schwarz, J. (1976) Biochim. Biophys.
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Modeling secondary structures and secondary structure linkages of protein sequences

2010 IEEE International Conference on Systems, Man and Cybernetics, 2010
In this paper we model protein secondary structures such as a-helices and b sheets and linkages thereof using passive electrical circuit components and obtain the frequency responses of these circuits. An analysis of the frequency responses of these model circuits shows that putative connections can be made between circuit behavior and known ...
openaire   +2 more sources

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