Results 131 to 140 of about 180,875 (351)
The MULTICOM toolbox for protein structure prediction
BMC Bioinformatics, 2012 Background As genome sequencing is becoming routine in biomedical research, the total number of protein sequences is increasing exponentially, recently reaching over 108 million. However, only a tiny portion of these proteins (i.e.
Cheng Jianlin +4 more
doaj +1 more source
A protein tertiary structure mimetic modulator of the Hippo signalling pathway
Nature Communications, 2020 Targeting the interaction between transcription factor TEAD and its co-repressor VGL4 is an attractive strategy to chemically modulate Hippo signaling.
Hélène Adihou +21 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Proteins: Structure, Function, and Bioinformatics, 2019 Scoring model structure is an essential component of protein structure prediction that can affect the prediction accuracy tremendously. Users of protein structure prediction results also need to score models to select the best models for their ...
Jonghun Won +4 more
semanticscholar +1 more source
Size Dependence of Protein Diffusion in the Cytoplasm of Escherichia coli
, 2010 Diffusion in the bacterial cytoplasm is regarded as the primary method of intracellular protein movement and must play a major role in controlling the rates of cell processes.
Mastroianni, G +5 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
PLoS Pathogens, 2018 As cell-invading molecular machinery, coronavirus spike proteins pose an evolutionary conundrum due to their high divergence. In this study, we determined the cryo-EM structure of avian infectious bronchitis coronavirus (IBV) spike protein from the γ ...
J. Shang +7 more
semanticscholar +1 more source
A computer system to perform structure comparison using TOPS representations of protein structure
, 2001 We describe the design and implementation of a fast topology–based method for protein structure comparison. The approach uses the TOPS topological representation of protein structure, aligning two structures using a common discovered pattern and ...
Viksna, J +3 more
core
Enhanced Honey Bees Colony Algorithms For Protein Tertiary Structure Prediction [PDF]
, 2011 There is no doubt about the role that protein plays in the biological processes inside the human body. Proteins are able to perform their biological functions when they fold into their tertiary structure.
Bahamish, Hesham Awadh Abdallah
core
The sodium-dependent D-glucose transport protein of Helicobacter pylori
, 2008 Helicobacter pylori is a gram-negative pathogenic microaerophile with a particular tropism for the mucosal surface of the gastric epithelium. Despite its obligatory microaerophilic character, it can metabolize D-glucose and/or D-galactose in both ...
Kim E. Bettaney +21 more
core +1 more source