Results 151 to 160 of about 180,875 (351)

'Never Mind a Barrel'

CHIMIA, 2001
The general usefulness of rigid-rod molecules rather than ?-sheets as molecular staves for the construction of artificial ?-barrels with preserved structural and functional plasticity is described.
Bodo Baumeister, Gopal Das, Naomi Sakai, Stefan Matile   +3 more
doaj  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Single-molecule chemical denaturation of riboswitches

, 2013
To date, single-molecule RNA science has been developed almost exclusively around the effect of metal ions as folding promoters and stabilizers of the RNA structure.
St-Pierre, Patrick, Penedo, J Carlos, Dubé, Audrey, Samuel, Ifor D W, St-Pierre, P, Samuel, Ifor David William, Lafontaine, Daniel, Dalgarno, Paul Allan, Bordello, Jorge, Morris, Rhodri, Bordello, J, Penedo, Carlos, Lafontaine, Daniel A, Dubé, A., Dalgarno, Paul A; id_orcid   +14 more
core   +1 more source

Finding protein sites using machine learning methods

Ingeniería e Investigación, 2003
The increasing amount of protein three-dimensional (3D) structures determined by x-ray and NMR technologies as well as structures predicted by computational methods results in the need for automated methods to provide inital annotations.
Jaime Leonardo Bobadilla Molina, Fernando Niño, Tobías Mojica   +2 more
doaj  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Alignment analysis of TMPRSS2 protein tertiary structure.

Alignment analysis of TMPRSS2 protein tertiary structure.
Marzieh Eskandarzadeh (18388767), Ali Mohebbi (4433587), Hanieh Zangi (18388770), Marzie Fatehi (18388773)   +3 more
core   +1 more source

tertiary structure of a protein

Citation: 'tertiary structure of a protein' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09785 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
openaire   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Enhancing protein-protein docking by new approaches to protein flexibility and scoring of docking hypotheses

, 2004
Zöllner FG. Enhancing protein-protein docking by new approaches to protein flexibility and scoring of docking hypotheses. Bielefeld (Germany): Bielefeld University; 2004.Für das Verständnis von biologischen Funktionen können Proteindockingverfahren ...
Frank G. Zöllner, Zöllner, Frank Gerrit   +1 more
core