Inspired by metal‐free carbonic anhydrases (CAs) that achieve efficient catalysis without metal cofactors, we herein report a sequence‐defined supramolecular peptoid platform that mimics metal‐free CAs and exhibits hydrolytic activity via a supramolecular assembly‐mediated proton‐transfer mechanism.
Progyateg Chakma +8 more
wiley +1 more source
Weakly basic electrolysed water combined with ultrasound for enhancing the binding and functional properties of Antarctic krill protein-gallic acid complexes. [PDF]
Wang J, Zhu D, Li R, Sun Y, Li Y.
europepmc +1 more source
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu +14 more
wiley +1 more source
Designing a chimeric multi-epitope vaccine against Candida auris using reverse vaccinology approach targeting the agglutinin-like protein N-terminal domain. [PDF]
Aljumaa MA +7 more
europepmc +1 more source
Nitride MXenes remain constrained by a persistent gap between computational prediction and experimental realization. This Review identifies the thermodynamic, kinetic, and chemical barriers limiting their synthesis, critically evaluates emerging fabrication routes, and proposes a multidimensional computational‐experimental framework to accelerate the ...
Naresh Varnakavi, Masoud Soroush
wiley +1 more source
Multilevel <i>in silico</i> structural analysis of WNT proteins. [PDF]
Midlovets K, Volkova N, Peka M.
europepmc +1 more source
Bioinspired Hydrogels with Broadly Programmable Mechanics for Soft‐Tissue Interfaces
Sea cucumber‐inspired gelatin hydrogels are formed by directional freezing and mechanically programmed through subsequent ionic treatment. Multiscale characterization and modeling link ion‐regulated chain interactions to directional load transfer within the aligned hierarchical architecture.
Youchao Teng +20 more
wiley +1 more source
Structure-Activity Relationship Analysis of Immunoassay Systems for (Fluoro)quinolones Detection. [PDF]
Chebotaev PP +4 more
europepmc +1 more source
Biodegradable 3D‐Printable and Coatable Antifouling Composites for Marine Applications
Marine biofouling damages submerged surfaces and raises greenhouse gas emissions. Biodegradable antifouling biocomposites were developed by hot‐mixing beeswax, Tween 80, and calcium stearate or stearic acid. Adjusting the component ratio enables processing via hot‐pressing, 3D‐printing, or dip‐coating.
Gabriele Corigliano +17 more
wiley +1 more source
ARTEM server: an online tool for nucleic acid 3D motif searches, 3D structure superposition and structure-based alignment. [PDF]
Sordyl D +4 more
europepmc +1 more source

