Results 201 to 210 of about 3,840,867 (319)

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

HCM-Associated MuRF1 Variants Compromise Ubiquitylation and Are Predicted to Alter Protein Structure. [PDF]

Int J Mol Sci
Chunthorng-Orn J, Noureddine M, Dawson PWJ, Lord SO, Ng J, Boyton L, Gehmlich K, Mohammed F, Lai YC.   +8 more
europepmc   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Correction: Cilia regeneration requires an RNA splicing factor from the ciliary base

Cell Regeneration, 2022
Kaiming Xu, Guangshuo Ou
doaj   +1 more source

The Use of Dansyl Chloride to Probe Protein Structure and Dynamics. [PDF]

Int J Mol Sci
Larson J, Tokmina-Lukaszewska M, Malone J, Hasenoehrl EJ, Kelly W, Fang X, White A, Patterson A, Bothner B.   +8 more
europepmc   +1 more source

On the Quaternary Structure of High-Molecular-Weight Proteins from the Bovine Eye Lens [PDF]

, 1975
Hans A. Kramps, A.L.H. Stols, Herman J. Hoenders, K. de Groot   +3 more
openalex   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Rational design of ¹⁹F NMR labelling sites to probe protein structure and interactions. [PDF]

Nat Commun
Streit JO, Chan SHS, Daya S, Christodoulou J.   +3 more
europepmc   +1 more source

Primary structure of protein l24 from the Escherichia coli ribosome [PDF]

, 1979
Brigitte Wittmann‐Liebold
openalex   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

FEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui, Ariel Kushmaro, Hana Barak, Anja Poehlein, Rolf Daniel, Hans‐Jürgen Mägert   +5 more
wiley   +1 more source