Results 201 to 210 of about 2,069,772 (318)

Review of protein structure-based analyses that illuminate plant stress mechanisms. [PDF]

Comput Struct Biotechnol J
Shahid F, Sen N, Rasni HN, Isa NM, Ma NL, Orengo C, Lam SD.   +6 more
europepmc   +1 more source

The Evolution of Protein Structures

Cold Spring Harbor Symposia on Quantitative Biology, 1987
C, Chothia, A M, Lesk
openaire   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Distance-AF improves predicted protein structure models by AlphaFold2 with user-specified distance constraints. [PDF]

Commun Biol
Zhang Y, Zhang Z, Kagaya Y, Terashi G, Zhao B, Xiong Y, Kihara D.   +6 more
europepmc   +1 more source

High-resolution structure analysis of ribosomal proteins from thermophilic organisms

, 2000
T. Nakashima, Motomasa Tanaka, Meng-Chao Yao, Masao Kimura, Isao Tanaka   +4 more
openalex   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Web-based GTalign: bridging speed and accuracy in protein structure analysis. [PDF]

Nucleic Acids Res
Dapkūnas J, Margelevičius M.
europepmc   +1 more source

3P-289 Correlation between RNA editing sites on amino acid residues and protein three-dimensional structures in plant organelles(The 46th Annual Meeting of the Biophysical Society of Japan)

, 2008
Mitiko Gō, Kei Yura
openalex   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

DeepFold-PLM: accelerating protein structure prediction via efficient homology search using protein language models. [PDF]

Bioinformatics
Kim M, Bae H, Jo G, Kim K, Lee SJ, Yoo J, Joo K.   +6 more
europepmc   +1 more source