Results 221 to 230 of about 12,004,907 (291)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Viro3D: a comprehensive database of virus protein structure predictions. [PDF]

Mol Syst Biol
Litvin U, Lytras S, Jack A, Robertson DL, Hughes J, Grove J.   +5 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

AlphaFold Protein Structure Database 2025: a redesigned interface and updated structural coverage. [PDF]

Nucleic Acids Res
Bertoni D, Tsenkov M, Magana P, Nair S, Pidruchna I, Querino Lima Afonso M, Midlik A, Paramval U, Lawal D, Tanweer A, Last M, Patel R, Laydon A, Lasecki D, Dietrich N, Tomlinson H, Žídek A, Green T, Kovalevskiy O, Lau A, Kandathil S, Bordin N, Sillitoe I, Mirdita M, Jones D, Orengo C, Steinegger M, Fleming JR, Velankar S.   +28 more
europepmc   +1 more source

<i>In Cellulo</i> Cysteine Umpolung for Protein Structure Probing. [PDF]

J Am Chem Soc
Hartmann P, Bohdan K, Vogelsang L, Marchionni D, Preisinger C, Vetere A, Dietz KJ, Ritter T.   +7 more
europepmc   +1 more source

Efficient protein structure generation with sparse denoising models. [PDF]

Nat Mach Intell
Jendrusch M, Korbel JO.
europepmc   +1 more source

Influence of Pulsed Electric Field Technology on Functionality and Protein Structure of Evaporated Skim Milk and Nonfat Dry Milk. [PDF]

Int J Mol Sci
Ryan EL, McDougal OM.
europepmc   +1 more source

Transient protein structure guides surface diffusion pathways for electron transport in membrane supercomplexes. [PDF]

Nat Commun
Chan CK, Nguyen J, Hryc CF, Gupta C, Guberman-Pfeffer MJ, Redding K, Dowhan W, Baker ML, Perez A, Mileykovskaya E, Singharoy A.   +10 more
europepmc   +1 more source

FlatProt: 2D visualization eases protein structure comparison. [PDF]

BMC Bioinformatics
Olenyi T, Carl C, Senoner T, Koludarov I, Rost B.   +4 more
europepmc   +1 more source

Protein structure shapes natural genetic variation and de novo adaptation

Jakobson CM, Van Elgort A, Aguilar-Rodríguez J, Jarosz DF.   +3 more
europepmc   +1 more source