Results 231 to 240 of about 12,004,907 (291)
Some of the next articles are maybe not open access.
Journal of the Society of Dyers and Colourists, 1939
THE structure of proteins is the major unsolved problem on the boundary of chemistry and biology to-day. We have not yet found the key to the problem, but in recent years a mass of new evidence and new lines of attack have enabled us to see it in a far more concrete and precise form, and to have some hope that we are near to solving it.
openaire +1 more source
THE structure of proteins is the major unsolved problem on the boundary of chemistry and biology to-day. We have not yet found the key to the problem, but in recent years a mass of new evidence and new lines of attack have enabled us to see it in a far more concrete and precise form, and to have some hope that we are near to solving it.
openaire +1 more source
Protein Structure Prediction and Structural Genomics
Science, 2001Genome sequencing projects are producing linear amino acid sequences, but full understanding of the biological role of these proteins will require knowledge of their structure and function. Although experimental structure determination methods are providing high-resolution structure information about a subset of the proteins, computational structure ...
D, Baker, A, Sali
openaire +2 more sources
2008
Protein structure prediction has matured over the past few years to the point that even fully automated methods can provide reasonably accurate three-dimensional models of protein structures. However, until now it has not been possible to develop programs able to perform as well as human experts, who are still capable of systematically producing better
AlLazikani B, Hill EE, Morea V
openaire +4 more sources
Protein structure prediction has matured over the past few years to the point that even fully automated methods can provide reasonably accurate three-dimensional models of protein structures. However, until now it has not been possible to develop programs able to perform as well as human experts, who are still capable of systematically producing better
AlLazikani B, Hill EE, Morea V
openaire +4 more sources
2016
This chapter explores the structures of proteins in more detail than thus far in this text. Building on the basic structural and physical chemistry of amino acids and protein conformations, it examines the features that stabilize native states. Proteins combine the unity of a common and repetitive mainchain with the variety available from a sequence of
openaire +1 more source
This chapter explores the structures of proteins in more detail than thus far in this text. Building on the basic structural and physical chemistry of amino acids and protein conformations, it examines the features that stabilize native states. Proteins combine the unity of a common and repetitive mainchain with the variety available from a sequence of
openaire +1 more source
Protein structure similarities
Current Opinion in Structural Biology, 2001Comparison of protein structures can reveal distant evolutionary relationships that would not be detected by sequence information alone. This helps to infer functional properties. In recent years, many methods for pairwise protein structure alignment have been proposed and are now available on the World Wide Web.
Patrice Koehl
exaly +3 more sources
The structure of protein evolution and the evolution of protein structure
Current Opinion in Structural Biology, 2008The observed distribution of protein structures can give us important clues about the underlying evolutionary process, imposing important constraints on possible models. The availability of results from an increasing number of genome projects has made the development of these models an active area of research.
openaire +2 more sources
Molecular Biotechnology, 2009
Web-based protein structure databases come in a wide variety of types and levels of information content. Those having the most general interest are the various atlases that describe each experimentally determined protein structure and provide useful links, analyses, and schematic diagrams relating to its 3D structure and biological function.
openaire +4 more sources
Web-based protein structure databases come in a wide variety of types and levels of information content. Those having the most general interest are the various atlases that describe each experimentally determined protein structure and provide useful links, analyses, and schematic diagrams relating to its 3D structure and biological function.
openaire +4 more sources