Results 151 to 160 of about 394,231 (262)

Improving protein structure prediction using templates and sequence embedding. [PDF]

Bioinformatics, 2023
Wu F, Jing X, Luo X, Xu J.
europepmc   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Novel De Novo DLL4 Missense and Highly Accurate Protein Structure Prediction in Adams-Oliver Type 6 Syndrome. [PDF]

Clin Case Rep
Cabrera R, Montañez MYB, Gil-Quiñones SR, Beltrán AM, Santiago-Tovar N, Contreras-Bravo N, Fonseca-Mendoza DJ, Restrepo CM, Morel A.   +8 more
europepmc   +1 more source

Ab initio protein structure prediction: the necessary presence of external force field as it is delivered by Hsp40 chaperone. [PDF]

BMC Bioinformatics, 2023
Roterman I, Stapor K, Konieczny L.
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Highly accurate protein structure prediction-based virtual docking pipeline accelerating the identification of anti-schistosomal compounds. [PDF]

PLoS Pathog
Cheng W, Gu M, Wang Y, Wang J, Li S, Chen G, Chen X, Oyeyemi OT, Hong Y, Hu W, Wang J.   +10 more
europepmc   +1 more source

Protein structure prediction with in-cell photo-crosslinking mass spectrometry and deep learning. [PDF]

Nat Biotechnol, 2023
Stahl K, Graziadei A, Dau T, Brock O, Rappsilber J.   +4 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Deep-learning-based single-domain and multidomain protein structure prediction with D-I-TASSER. [PDF]

Nat Biotechnol
Zheng W, Wuyun Q, Li Y, Liu Q, Zhou X, Peng C, Zhu Y, Freddolino L, Zhang Y.   +8 more
europepmc   +1 more source

Protein Structure Prediction with Mass Spectrometry Data. [PDF]

Annu Rev Phys Chem, 2022
Biehn SE, Lindert S.
europepmc   +1 more source