Results 161 to 170 of about 417,581 (263)

Highly accurate protein structure prediction-based virtual docking pipeline accelerating the identification of anti-schistosomal compounds. [PDF]

PLoS Pathog
Cheng W, Gu M, Wang Y, Wang J, Li S, Chen G, Chen X, Oyeyemi OT, Hong Y, Hu W, Wang J.   +10 more
europepmc   +1 more source

Protein structure prediction on the Web [PDF]

Nature Biotechnology, 1997
openaire   +2 more sources

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Deep-learning-based single-domain and multidomain protein structure prediction with D-I-TASSER. [PDF]

Nat Biotechnol
Zheng W, Wuyun Q, Li Y, Liu Q, Zhou X, Peng C, Zhu Y, Freddolino L, Zhang Y.   +8 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Advancements in one-dimensional protein structure prediction using machine learning and deep learning. [PDF]

Comput Struct Biotechnol J
Alanazi W, Meng D, Pollastri G.
europepmc   +1 more source

Protein Structure Prediction and Structural Annotation of Proteomes [PDF]

, 2013
Roche, Daniel Barry, Buenavista, Maria Teresa, McGuffin, Liam James   +2 more
openaire   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

LightRoseTTA: High-Efficient and Accurate Protein Structure Prediction Using a Light-Weight Deep Graph Model. [PDF]

Adv Sci (Weinh)
Wang X, Zhang T, Liu G, Cui Z, Zeng Z, Long C, Zheng W, Yang J.   +7 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source