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Current Opinion in Chemical Biology, 2001
The prediction of protein structure, based primarily on sequence and structure homology, has become an increasingly important activity. Homology models have become more accurate and their range of applicability has increased. Progress has come, in part, from the flood of sequence and structure information that has appeared over the past few years, and ...
B, Al-Lazikani +3 more
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The prediction of protein structure, based primarily on sequence and structure homology, has become an increasingly important activity. Homology models have become more accurate and their range of applicability has increased. Progress has come, in part, from the flood of sequence and structure information that has appeared over the past few years, and ...
B, Al-Lazikani +3 more
openaire +2 more sources
Current Opinion in Biotechnology, 1998
Genome sequencing projects continue to provide a flood of new protein sequences, and prediction methods remain an important means of adding structural information. Recently, there have been advances in secondary structure prediction, which feed, in turn, into improved fold recognition algorithms.
D R, Westhead, J M, Thornton
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Genome sequencing projects continue to provide a flood of new protein sequences, and prediction methods remain an important means of adding structural information. Recently, there have been advances in secondary structure prediction, which feed, in turn, into improved fold recognition algorithms.
D R, Westhead, J M, Thornton
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Science, 1996
Elizabeth Pennisi's Research News article “Teams tackle protein prediction” ([26 July, p. 426][1]) describes an ongoing project, known as CASP (for Critical Assessment of Techniques for Protein Structure Prediction) ([1][2]), to provide researchers who model protein structures with the opportunity to jointly make bona fide predictions, announced before
S A, Benner, D L, Geroff, J D, Rozzell
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Elizabeth Pennisi's Research News article “Teams tackle protein prediction” ([26 July, p. 426][1]) describes an ongoing project, known as CASP (for Critical Assessment of Techniques for Protein Structure Prediction) ([1][2]), to provide researchers who model protein structures with the opportunity to jointly make bona fide predictions, announced before
S A, Benner, D L, Geroff, J D, Rozzell
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Protein Structure Prediction and Structural Genomics
Science, 2001Genome sequencing projects are producing linear amino acid sequences, but full understanding of the biological role of these proteins will require knowledge of their structure and function. Although experimental structure determination methods are providing high-resolution structure information about a subset of the proteins, computational structure ...
D, Baker, A, Sali
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Protein structure prediction and design [PDF]
, 1998 Proteins have a unique native conformation, which can be proven in many instances to be determined by the amino acid sequence alone. The folding problem, that is the understanding of how the amino acid sequence directs folding, is still unsolved, despite more than 30 years of effort. However, many new methods have appeared in the past few years.
Morea V, Leplae R, Tramontano, A
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2008
Protein structure prediction has matured over the past few years to the point that even fully automated methods can provide reasonably accurate three-dimensional models of protein structures. However, until now it has not been possible to develop programs able to perform as well as human experts, who are still capable of systematically producing better
AlLazikani B, Hill EE, Morea V
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Protein structure prediction has matured over the past few years to the point that even fully automated methods can provide reasonably accurate three-dimensional models of protein structures. However, until now it has not been possible to develop programs able to perform as well as human experts, who are still capable of systematically producing better
AlLazikani B, Hill EE, Morea V
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Prediction of Protein Structure
2004Publisher Summary This chapter describes the extraction of structural information from protein sequence. The deduced sequences of proteins provide invaluable insights into the functions of those proteins and the evolution of the organisms producing those proteins.
Robert H, Kretsinger +2 more
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Protein structure prediction in 2002
Current Opinion in Structural Biology, 2002Central issues concerning protein structure prediction have been highlighted by the recently published summary of the fourth community-wide protein structure prediction experiment (CASP4). Although sequence/structure alignment remains the bottleneck in comparative modeling, there has been substantial progress in fully automated remote homolog detection
David Baker +2 more
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Protein Secondary Structure Prediction
Current Protocols in Protein Science, 1995AbstractThis unit describes procedures developed for predicting protein structure from the amino acid sequence. The first of the four sections is an overview and brief history of structure prediction schemes. The second section describes four distinct prediction schemes, with emphasis on their differences.
S R, Krystek, W J, Metzler, J, Novotny
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Approaches to prediction of protein structure
2011 9th IEEE/ACS International Conference on Computer Systems and Applications (AICCSA), 2011Protein structure prediction (PSP) is one of the most important and challenging problems in bioinformatics today. This is due to the fact that the biological function of the protein is determined by its structure. While there is a gap between the number of known protein sequences and the number of known structures, protein structure prediction aims at ...
Walaa Fathy Ahmed, Walid E. Gomaa
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