Results 221 to 230 of about 417,581 (263)

Predicting structures for genome proteins

Current Opinion in Structural Biology, 1999
Assigning three-dimensional protein folds to genome sequences is essential to understanding protein function. Although experimental three-dimensional structures are currently available for only a very small fraction of these sequences, computational fold assignment is able to assign folds to 20-30% of the sequences in various genomes.
D, Fischer, D, Eisenberg
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Predicting Protein Structures Accurately

Science, 2004
In their Research Article “Design of a novel globular protein fold with atomic-level accuracy,” B. Kuhlman et al. describe an extremely successful attempt to design a new protein (Top7) that folds to a predefined structure (21 Nov, p. [1364][1]).
Marcin, von Grotthuss, Lucjan S, Wyrwicz, Jakub, Pas, Leszek, Rychlewski   +3 more
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Protein structure prediction

Biochimie, 1990
Current methods developed for predicting protein structure are reviewed. The most widely used algorithms of Chou and Fasman and Garnier et al for predicting secondary structure are compared to the most recent ones including sequence similarity methods, neural network, pattern recognition or joint prediction methods.
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Toolbox for Protein Structure Prediction

2016
Protein tertiary structure prediction algorithms aim to predict, from amino acid sequence, the tertiary structure of a protein. In silico protein structure prediction methods have become extremely important, as in vitro-based structural elucidation is unable to keep pace with the current growth of sequence databases due to high-throughput next ...
Roche, Daniel Barry, Mcguffin, Liam James   +1 more
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Agent-based protein structure prediction [PDF]

Multiagent and Grid Systems, 2007
A protein is identified by a finite sequence of amino acids, each of them chosen from a set of 20 elements. The Protein Structure Prediction Problem is the problem of predicting the 3D native conformation of a protein, when its sequence of amino acids is known.
Luca Bortolussi, Agostino Dovier, Federico Fogolari   +2 more
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Protein Tertiary Structure Prediction

Current Protocols in Protein Science, 2000
AbstractThis unit addresses how to predict the tertiary structure of a protein from its amino acid sequence using computational methods. Three types of prediction methods‐‐homology modeling, fold recognition, and ab initio prediction‐‐are introduced.
D, Xu, Y, Xu
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Prediction of Protein Structural Classes

Critical Reviews in Biochemistry and Molecular Biology, 1995
A protein is usually classified into one of the following five structural classes: alpha, beta, alpha + beta, alpha/beta, and zeta (irregular). The structural class of a protein is correlated with its amino acid composition. However, given the amino acid composition of a protein, how may one predict its structural class?
K C, Chou, C T, Zhang
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Structure prediction of the RPE65 protein

Journal of Theoretical Biology, 2006
The RPE65 protein is located in the retinal pigment epithelial cells and plays an important role in the visual cycle. Although numerous experimental results demonstrate that it participates in the visual cycle, its detailed structure and function are not clear yet because of difficulties in isolation and crystallization.
Hao, Guo, Chong, Zheng, Elizabeth R, Gaillard   +2 more
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Structure Predictions for Membrane Proteins

1987
To predict the folding of membrane proteins one usually starts by identifying stretches of ∿ 20 hydrophobic residues on the amino acid sequence. Folded in an α-helix, these residues would span the hydrocarbon core of the lipid bilayer. Following Kyte and Doolittle (1982), a hydrophobicity index h is attributed to each amino acid residue and the mean ...
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Assessment of Protein Structure Predictions

2008
Not available.
CAPRIOTTI, EMIDIO, Marti Renom, M. A.
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