Results 51 to 60 of about 4,305,499 (240)
Subcellular localization of CsGAIP protein.
, 2014 (A) Alignment of the N-terminal 200–300 amino acid residues of CsGAIP with AtRGA and AtGAI. The black line indicates the highly conserved nuclear localization signal (NLS) domain.
Jingbo An (535578) +6 more
core +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
BMC Genomics, 2018 Background Apoptosis is associated with some human diseases, including cancer, autoimmune disease, neurodegenerative disease and ischemic damage, etc.
Bin Yu +6 more
doaj +1 more source
Quantification of fusion protein subcellular localization in zebrafish somatic cells.
, 2018 Quantification of fusion protein subcellular localization in zebrafish somatic cells.
KathyAnn Lee (5484533) +4 more
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Nano Convergence, 2018 In this article, we elaborate the application of thermal decomposition based synthesis of Fe3O4 superparamagnetic nanoparticle (SPMNP) in subcellular fractionation context.
Deepak B. Thimiri Govinda Raj +1 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Subcellular Fractionation of Cultured Human Cell Lines
Bio-Protocol, 2013 Subcellular localization is crucial for the proper functioning of a protein. Deregulation of subcellular localization may lead to pathological consequences and result in diseases like cancer.
Zhuoyou Yu, Zhiguang Huang, Maria Lung
doaj +1 more source
Subcellular localization of OsPT4 protein.
, 2015 Subcellular localization of OsPT4 protein was determined in rice protoplasts. The confocal image was acquired using a confocal laser scanning microscope (TCS SP2).
Jing Yuan (217967) +6 more
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source