Results 221 to 230 of about 101,248 (253)

Recent progress in protein subcellular location prediction

Analytical Biochemistry, 2007
0003-2697/$ see front matter 2007 Elsevier Inc. All rights reserve doi:10.1016/j.ab.2007.07.006 * Corresponding author. E-mail address: kcchou@gordonlifescience.org (K.-C. Chou). With a typical size of 10 lm and a typical mass of 1 ng, the cell is deemed to be the most basic structural and functional unit of all living organisms and often is called a ‘‘
Kuo-Chen, Chou, Hong-Bin, Shen
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Improved Comparison of Protein Subcellular Location Patterns

3rd IEEE International Symposium on Biomedical Imaging: Macro to Nano, 2006., 2006
A common task in cell and molecular biology is to evaluate the difference or similarity among location patterns under different circumstances. Our previous work has described an automated method to objectively compare any pair of subcellular location patterns using well-characterized numerical features.
Ting Zhao, Stalia Soto, Robert F. Murphy
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Location Proteomics: Systematic Determination of Protein Subcellular Location

2009
Proteomics seeks the systematic and comprehensive understanding of all aspects of proteins, and location proteomics is the relatively new subfield of proteomics concerned with the location of proteins within cells. This review provides a guide to the widening selection of methods for studying location proteomics and integrating the results into systems
Justin, Newberg, Juchang, Hua, Robert F, Murphy   +2 more
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Prediction of subcellular locations of proteins: Where to proceed?

PROTEOMICS, 2010
Abstract Since the proposal of the signal hypothesis on protein subcellular sorting, a number of computational analyses have been performed in this field. A typical example is the development of prediction algorithms for the subcellular localization sites of input protein sequences.
Kenichiro, Imai, Kenta, Nakai
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Automated Interpretation of Protein Subcellular Location Patterns

2006
Proteomics is a major current focus of biomedical research, and location proteomics is the important branch of proteomics that systematically studies the subcellular distributions for all proteins expressed in a given cell type. Fluorescence microscopy of labeled proteins is currently the main methodology to obtain location information.
Xiang, Chen, Robert F, Murphy
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Predictability of protein subcellular locations by pattern recognition techniques

2010 Annual International Conference of the IEEE Engineering in Medicine and Biology, 2010
An analysis of the predictability of subcellular locations is performed by using simple pattern recognition techniques in an attempt to capture the real dimensions of the problem at hand. Results show that there are some particular locations that does not need of high complexity classification models to be predicted with high accuracies, and some ...
J A, Jaramillo-Garzon, A, Perera-Lluna, C G, Castellanos-Dominguez   +2 more
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Support Vector Machines for Prediction of Protein Subcellular Location

Molecular Cell Biology Research Communications, 2000
Support Vector Machine (SVM), which is one kind of learning machines, was applied to predict the subcellular location of proteins from their amino acid composition. In this research, the proteins are classified into the following 12 groups: (1) chloroplast, (2) cytoplasm, (3) cytoskeleton, (4) endoplasmic reticulum, (5) extracall, (6) Golgi apparatus, (
Y D, Cai, X J, Liu, X B, Xu , K C, Chou
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Artificial Neural Network Model for Predicting Protein Subcellular Location

Computers & Chemistry, 2002
The function of a protein is closely correlated to its subcellular location. Is it possible to utilize a bioinformatics method to predict the protein subcellular location? To explore this problem, proteins are classified into 12 groups (Protein Eng.
Yudong Cai, Kuo-Chen Chou, Xiao-Jun Liu
exaly   +3 more sources

Object Type Recognition for Automated Analysis of Protein Subcellular Location [PDF]

IEEE Transactions on Image Processing, 2005
The new field of location proteomics seeks to provide a comprehensive, objective characterization of the subcellular locations of all proteins expressed in a given cell type. Previous work has demonstrated that automated classifiers can recognize the patterns of all major subcellular organelles and structures in fluorescence microscope images with high
Robert F. Murphy, Michael V Boland, R F Murphy   +2 more
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Predicting protein subcellular location by fusing multiple classifiers

Journal of Cellular Biochemistry, 2006
AbstractOne of the fundamental goals in cell biology and proteomics is to identify the functions of proteins in the context of compartments that organize them in the cellular environment. Knowledge of subcellular locations of proteins can provide key hints for revealing their functions and understanding how they interact with each other in cellular ...
Kuo-Chen, Chou, Hong-Bin, Shen
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