Results 31 to 40 of about 101,248 (253)

A multiresolution approach to automated classification of protein subcellular location images

open access: yesBMC Bioinformatics, 2007
Background Fluorescence microscopy is widely used to determine the subcellular location of proteins. Efforts to determine location on a proteome-wide basis create a need for automated methods to analyze the resulting images.
Srinivasa Gowri   +6 more
doaj   +1 more source

A multi-label classifier for predicting the subcellular localization of gram-negative bacterial proteins with both single and multiple sites. [PDF]

open access: yesPLoS ONE, 2011
Prediction of protein subcellular localization is a challenging problem, particularly when the system concerned contains both singleplex and multiplex proteins. In this paper, by introducing the "multi-label scale" and hybridizing the information of gene
Xuan Xiao, Zhi-Cheng Wu, Kuo-Chen Chou
doaj   +1 more source

A new method for predicting the subcellular localization of eukaryotic proteins with both single and multiple sites: Euk-mPLoc 2.0. [PDF]

open access: yesPLoS ONE, 2010
Information of subcellular locations of proteins is important for in-depth studies of cell biology. It is very useful for proteomics, system biology and drug development as well.
Kuo-Chen Chou, Hong-Bin Shen
doaj   +1 more source

Esub8: A novel tool to predict protein subcellular localizations in eukaryotic organisms

open access: yesBMC Bioinformatics, 2004
Background Subcellular localization of a new protein sequence is very important and fruitful for understanding its function. As the number of new genomes has dramatically increased over recent years, a reliable and efficient system to predict protein ...
Liu Bing   +3 more
doaj   +1 more source

Predicting the subcellular location of prokaryotic proteins with DeepLocPro [PDF]

open access: yesBioinformatics
Abstract Protein subcellular location prediction is a widely explored task in bioinformatics because of its importance in proteomics research. We propose DeepLocPro, an extension to the popular method DeepLoc, tailored specifically to archaeal and bacterial organisms.
Jaime Moreno   +3 more
openaire   +5 more sources

Adaptive Multiresolution Techniques for Subcellular Protein Location Classification [PDF]

open access: yes2006 IEEE International Conference on Acoustics Speed and Signal Processing Proceedings, 2006
We propose an adaptive multiresolution (MR) approach for classification of fluorescence microscopy images of subcellular protein locations, providing biologically relevant information. These images have highly localized features both in space and frequency which naturally leads us to MR tools.
Gowri Srinivasa   +4 more
openaire   +2 more sources

Protein sequence information extraction and subcellular localization prediction with gapped k-Mer method

open access: yesBMC Bioinformatics, 2019
Background Subcellular localization prediction of protein is an important component of bioinformatics, which has great importance for drug design and other applications.
Yu-hua Yao   +8 more
doaj   +1 more source

TargetDB: a database of peptides targeting proteins to subcellular locations [PDF]

open access: yesBioinformatics, 1999
TargetDB is a relational database designed to represent data on protein targeting sequences, mutant signals, subcellular targets and source organisms.TargetDB is accessible at http://molbio.nmsu.edu:81. The web interface supports both direct data authoring and database query functions.moconnel@nmsu.
T. Wei, Michael O'Connell
openaire   +3 more sources

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Prediction of protein subcellular localization using support vector machine with the choice of proper kernel

open access: yesBioTechnologia, 2017
The prediction of subcellular locations of proteins can provide useful hints for revealing their functions as well as for understanding the mechanisms of some diseases and, finally, for developing novel drugs.
Al Mehedi Hasan   +2 more
doaj   +1 more source

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