Results 1 to 10 of about 6,092,811 (364)

Heterotrimeric G protein subunits differentially respond to endoplasmic reticulum stress in Arabidopsis. [PDF]

open access: yesPlant Signal Behav, 2015
Canonical heterotrimeric G proteins in eukaryotes are major components that localize at plasma membrane and transmit extracellular stimuli into the cell. Genome of a seed plant Arabidopsis thaliana encodes at least one Gα (GPA1), one Gβ (AGB1), and 3 Gγ (
Cho Y, Yu CY, Iwasa T, Kanehara K.
europepmc   +2 more sources

Protein synthesis by ribosomes with tethered subunits [PDF]

open access: yesNature, 2015
The ribosome is a ribonucleoprotein machine responsible for protein synthesis. In all kingdoms of life it is composed of two subunits, each built on its own ribosomal RNA (rRNA) scaffold. The independent but coordinated functions of the subunits, including their ability to associate at initiation, rotate during elongation, and dissociate after protein ...
C. Orelle   +5 more
semanticscholar   +4 more sources

Understanding protein-complex assembly through grand canonical maximum entropy modeling [PDF]

open access: yesPhysical Review Research, 2021
Inside a cell, heterotypic proteins assemble in inhomogeneous, crowded systems where the abundance of these proteins vary with cell types. While some protein complexes form putative structures that can be visualized with imaging, there are far more ...
Andrei G. Gasic   +2 more
doaj   +2 more sources

Protein Design is a Key Factor for Subunit-subunit Association [PDF]

open access: yesarXiv, 1999
Fundamental questions about the role of the quaternary structures are addressed using a statistical mechanics off-lattice model of a dimer protein. The model, in spite of its simplicity, captures key features of the monomer-monomer interactions revealed by atomic force experiments.
C. CLEMENTI, P. CARLONI, MARITAN, AMOS
arxiv   +7 more sources

Kingdom-specific lipid unsaturation calibrates sequence evolution in membrane arm subunits of eukaryotic respiratory complexes [PDF]

open access: yesNature Communications
Sequence evolution of protein complexes (PCs) is constrained by protein-protein interactions (PPIs). PPI-interfaces are predominantly conserved and hotspots for disease-related mutations.
Pooja Gupta   +11 more
doaj   +2 more sources

Regulation of HCN Channels by Protein Interactions

open access: yesFrontiers in Physiology, 2022
Hyperpolarization-activated, cyclic nucleotide-sensitive (HCN) channels are key regulators of subthreshold membrane potentials in excitable cells.
Colin H. Peters   +4 more
doaj   +1 more source

Quantitative N-Glycan Profiling of Therapeutic Monoclonal Antibodies Performed by Middle-Up Level HILIC-HRMS Analysis

open access: yesPharmaceutics, 2021
The identification and accurate quantitation of the various glycoforms contained in therapeutic monoclonal antibodies (mAbs) is one of the main analytical needs in the biopharmaceutical industry, and glycosylation represents a crucial critical quality ...
Bastiaan L. Duivelshof   +7 more
doaj   +1 more source

Two-Dimensional Blue Native/SDS Polyacrylamide Gel Electrophoresis for Analysis of Brazilian Bothrops Snake Venoms

open access: yesToxins, 2022
Viperidae snakes are the most important agents of snakebites in Brazil. The protein composition of snake venoms has been frequently analyzed by means of electrophoretic techniques, but the interaction of proteins in venoms has barely been addressed.
Natacha Ferreira de Oliveira   +2 more
doaj   +1 more source

Molecular and chemical analysis of the protein subunits and fractions of sesame meal in comparison to cottonseed meal and soybean meal using SDS-Page electrophoresis and CNCPS methods [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2013
In this research, two methods including SDS-Page electrophoresis and CNCPS were used to study the protein subunits and fractions of sesame meal in comparison to cottonseed meal and soybean meal.
Amin Khezri
doaj   +1 more source

COVID-19 Vaccines: An Updated Overview of Different Platforms

open access: yesBioengineering, 2022
Vaccination has been identified as a critical method of disease control in the context of the current COVID-19 pandemic. The goal of this review is to update information on vaccine development and to identify areas of concern that require further ...
Dmitry Kudlay   +2 more
doaj   +1 more source

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