HSP70 governs permeability and mechanotransduction in primary human endothelial cells
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Effects of high-molecular-weight glutenin subunit on hard-steamed bread quality
IntroductionSteamed bread (SB) is a daily food in many countries in the world, but the relationship between HMW-GS and the quality of SB remain unclear.MethodsThis study investigated the effects of 12 subunit combinations on the characteristics of SB ...
Jing Zhao +10 more
doaj +1 more source
Models for Cooperative Effects in Proteins Containing Subunits
Mary E. Kirtley, Daniel E. Koshland
openalex +1 more source
A Model for the Chemical Interactions of Adenosine 3':5'-Monophosphate with the R Subunit of Protein Kinase Type I. Refinement of the Cyclic Phosphate Binding moiety of Protein Kinase Type I [PDF]
Bernd Jastorff +2 more
openalex +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Serial perturbation of MinK in IKs implies an alpha-helical transmembrane span traversing the channel corpus. [PDF]
I(Ks) channels contain four pore-forming KCNQ1 subunits and two accessory MinK subunits. MinK influences surface expression, voltage-dependence of gating, conduction, and pharmacology to yield the attributes characteristic of native channels in heart ...
Chen, Haijun, Goldstein, Steve AN
core
Yeast Telomerase RNA Flexibly Scaffolds Protein Subunits: Results and Repercussions. [PDF]
Zappulla DC.
europepmc +1 more source
Interaction between Protein Subunits from Model Studies
Jehuda Feitelson
openalex +1 more source
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah +8 more
wiley +1 more source
Supercomplex-Associated Cox26 Protein Binds to Cytochrome \u3cem\u3ec\u3c/em\u3e Oxidase [PDF]
Here we identified a hydrophobic 6.4 kDa protein, Cox26, as a novel component of yeast mitochondrial supercomplex comprising respiratory complexes III and IV.
Angerer, Heike +8 more
core +1 more source

