Results 251 to 260 of about 708,409 (312)

APOE‐stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease

Advanced Science, EarlyView.
A large‐scale multiomic dataset (proteomic and metabolomic) comprising 3,060 plasma samples were analyzed to identify proteins, metabolites, pathways, and protein‐associated drugs linked to Alzheimer’s Disease (AD) independently of apolipoprotein E (APOE). AD was associated with a distinct molecular signature that captures.
Fuhai Li, Yike Chen, Daniel Western, Muhammad Ali, Menghan Liu, Katherine Gong, Ying Xu, Joseph Lowery, David M. Holtzman, Chloe Robins, John D. Eicher, Yen‐Ning Huang, ShiWei Liu, Tamina Park, Andrew J. Saykin, Kwangsik Nho, Mahdi Moqri, Richard C. Mohs, Amelia Farinas, Patricia Moran‐Losada, Hamilton Se‐Hwee Oh, Tony Wyss‐Coray, Carlos Cruchaga   +22 more
wiley   +1 more source

The Role of GABA and Its Receptors in Temporal Lobe Epilepsy. [PDF]

Biomolecules
Sperk G, Pirker S.
europepmc   +1 more source

KDM4A Erases the H3R17me2a Mark, Facilitating Chromosome Condensation

Advanced Science, EarlyView.
This study reveals a reversible histone modification switch governing chromosome condensation during mitosis. PKCα‐activated KDM4A removes H3R17me2a, permitting Suv39h1‐driven H3K9me3 deposition. This epigenetic transition recruits the chromosomal passenger complex and triggers Aurora B‐dependent H3S10 phosphorylation, coordinating chromatin remodeling
Yena Cho, Jee Won Hwang, Gyu Hwan Hyun, Sangkyu Lee, Dae‐Geun Song, Su‐Nam Kim, Yong Kee Kim   +6 more
wiley   +1 more source

Protein-interaction network analysis reveals the role of Prp19 splicing factor in transcription of both intron-containing and intron-lacking genes. [PDF]

PLoS Genet
Dwyer K, Essak MA, Awada A, Dhoondia Z, Ansari A.   +4 more
europepmc   +1 more source

Structure of a specialized 70S initiation complex. [PDF]

Nucleic Acids Res
Arpin D, Roy B, Naeem FM, Fredrick K, Ortega J.   +4 more
europepmc   +1 more source

Dual-Color Expansion Microscopy of Membrane Proteins Using Bioorthogonal Labeling. [PDF]

Nano Lett
Edwards S, Meineke B, Bauer S, Blom H, Elsässer S, Brismar H.   +5 more
europepmc   +1 more source

Roles of mitochondrial complexes in non-alcoholic fatty liver disease. [PDF]

Front Mol Biosci
Wang K, Wang L, Ning J, Li D.
europepmc   +1 more source

Cooperation of Transcription Factor PAX6 with Chromatin-Remodeling Complex BAF During Embryonic Development in Mammals. [PDF]

Cell Mol Neurobiol
Azieva A, Vasilyeva T, Maksimenko O, Davydenko K, Zinchenko R, Marakhonov A.   +5 more
europepmc   +1 more source

Purification and characterization of recombinant human translation initiation factor eIF3. [PDF]

Protein Sci
Diaz-Lopez I, Gordiyenko Y, Zuber PK, Li X, Ramakrishnan V.   +4 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Platelet Microtubule Subunit Proteins

Thrombosis and Haemostasis, 1979
SummaryBlood platelets contain microtubule proteins (tubulin and HMWs) which can be polymerised “in vitro” to form structures which resemble the microtubules seen in the intact platelet. Platelet tubulin is composed of two non-identical subunits a and p tubulin which have molecular weights around 55,000 but can be resolved in alkaline SDS ...
A G, Castle, N, Crawford
openaire   +3 more sources