Results 181 to 190 of about 1,784,597 (218)

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Sirtuin 2 inhibits global protein synthesis via Rheb-GTPase degradation. [PDF]

EMBO Rep
Shrama A, Zi Y, Pandit AS, Jha K, Sinha VK, Nagesh D, Shivanaiah B, Ravi V, Ghosh S, Khan D, Prabhashankar AB, Sumi TS, Rajpurohit S, Ningaraju S, Raghu S, Srivastava A, Singh M, Lin H, Sundaresan NR.   +18 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Neurons with granulovacuolar degeneration bodies are resilient to tau-induced protein synthesis impairment. [PDF]

Sci Adv
Smits JFM, Ligthart TW, Jorge-Oliva M, Middelhoff S, Schipper F, Pita-Illobre D, Li KW, Scheper W.   +7 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Toosendanin suppresses acute myeloid leukemia by targeting DDX5/c-Myc axis to inhibit protein synthesis. [PDF]

J Transl Med
He X, Chen Z, Luo J, Chen H, Hou Y, Liu D, Liu Y.   +6 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Structural insights into the recruitment of viral type 2 IRES to ribosomal preinitiation complex for protein synthesis. [PDF]

Elife
Das D, Hussain T.
europepmc   +1 more source

Author Correction: Sirtuin 2 inhibits global protein synthesis via Rheb-GTPase degradation. [PDF]

EMBO Rep
Shrama A, Zi Y, Pandit AS, Jha K, Sinha VK, Nagesh D, Shivanaiah B, Ravi V, Ghosh S, Khan D, Prabhashankar AB, Sumi TS, Rajpurohit S, Ningaraju S, Raghu S, Srivastava A, Singh M, Lin H, Sundaresan NR.   +18 more
europepmc   +1 more source