Results 191 to 200 of about 7,364,139 (305)

Myofibrillar protein accumulation but reduced protein synthesis in PDCD4-depleted myotubes. [PDF]

PLoS One
Mora S, Alihemmat L, Davari LD, Ataie T, Mehranjani PN, Flewwelling L, Cheng AJ, Adegoke OAJ.   +7 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Hippocampal astrocytic GAT-3 blockade impairs protein synthesis and spatial memory dynamics. [PDF]

Commun Biol
Riboldi JG, Iribarne J, Renfijes MM, Igaz LM, Moncada D, Viola H.   +5 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Retraction Note: Novel magnetic organic–inorganic hybrids based on aromatic polyamides and ZnFe2O4 nanoparticles with biological activity

Scientific Reports
Reza Eivazzadeh-Keihan, Mostafa Ghafori Gorab, Hooman Aghamirza Moghim Aliabadi, Mohammad mahdavi, Ali Reza Akbarzadeh, Ali Maleki, Hossein Ghafuri   +6 more
doaj   +1 more source

The importance of nonsense errors: Estimating the rates and implications of ribosome drop-off during protein synthesis. [PDF]

PLoS Genet
Cope AL, Pak D, Gilchrist MA.
europepmc   +1 more source

Retraction Note: A novel, bioactive and antibacterial scaffold based on functionalized graphene oxide with lignin, silk fibroin and ZnO nanoparticles

Scientific Reports
Reza Eivazzadeh-Keihan, Ensiye Zare-Bakheir, Hooman Aghamirza Moghim Aliabadi, Mostafa Ghafori Gorab, Hossein Ghafuri, Ali Maleki, Hamid Madanchi, Mohammad Mahdavi   +7 more
doaj   +1 more source

Replating Induces mTOR-Dependent Rescue of Protein Synthesis in Charcot-Marie-Tooth Diseased Neurons. [PDF]

eNeuro
Koenig J, McGuire A, Homedan Y, Alberhasky J, Summers DW.   +4 more
europepmc   +1 more source