Results 241 to 250 of about 11,322,924 (398)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Transcriptional regulation of protein synthesis by mediator kinase represents a therapeutic vulnerability in MYC-driven medulloblastoma. [PDF]

open access: yesNat Commun
Wang D   +14 more
europepmc   +1 more source

Studies on the Synthesis of Protein Analogus. XII-XV. XII. Preparation of Poly-γ-aminobutyric Acid and Poly-γ-aminobutyryl-DL-alanine.

open access: diamond, 1956
野口 順蔵   +7 more
openalex   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Integrated muscle protein synthesis during disuse and rehabilitation in late-midlife adults. [PDF]

open access: yesAm J Physiol Regul Integr Comp Physiol
Kilroe SP   +10 more
europepmc   +1 more source

Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2007
R. Deberardinis   +6 more
semanticscholar   +1 more source

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