Results 61 to 70 of about 11,322,924 (398)
Microbiology Spectrum, 2023 The SARS-CoV-2 virion is composed of four structural proteins: spike (S), nucleocapsid (N), membrane (M), and envelope (E). E spans the membrane a single time and is the smallest, yet most enigmatic of the structural proteins.
Hope Waisner +5 more
doaj +1 more source
Metabolic properties of the products of mitochondrial protein synthesis in HeLa cells [PDF]
, 1977 The metabolic behavior of the mitochondrial protein synthesis products has been investigated in HeLa cells. Particular attention was given to the four major electrophoretic components (designated as Nos. 2, 3, 5, and 8) of the 10 previously identified as
Attardi, Giuseppe, Costantino, Paolo
core
The Regulatory Role of MeAIB in Protein Metabolism and the mTOR Signaling Pathway in Porcine Enterocytes. [PDF]
, 2018 Amino acid transporters play an important role in cell growth and metabolism. MeAIB, a transporter-selective substrate, often represses the adaptive regulation of sodium-coupled neutral amino acid transporter 2 (SNAT2), which may act as a receptor and ...
Ji, Peng +5 more
core +2 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
The enzymatic synthesis of protein. IV. The effect of concentration on peptic synthesis [PDF]
, 1925 In the enzymatic hydrolysis and synthesis of proteins in vitro, the important factor, the factor upon which the direction and the degree of the reaction are dependent, is not the relative concentration of water, but the concentration of material in ...
Borsook, Henry, Wasteneys, Hardolph
core
Deterministic and stochastic descriptions of gene expression dynamics
, 2012 A key goal of systems biology is the predictive mathematical description of gene regulatory circuits. Different approaches are used such as deterministic and stochastic models, models that describe cell growth and division explicitly or implicitly etc ...
A.M. Walczak +51 more
core +1 more source
mTOR coordinates protein synthesis, mitochondrial activity and proliferation
Cell Cycle, 2015 Protein synthesis is one of the most energy consuming processes in the cell. The mammalian/mechanistic target of rapamycin (mTOR) is a serine/threonine kinase that integrates a multitude of extracellular signals and intracellular cues to drive growth and
M. Morita +6 more
semanticscholar +1 more source
Funnels, pathways, and the energy landscape of protein folding: A synthesis [PDF]
Proteins: Structure, Function, and Bioinformatics, 1994 The understanding, and even the description of protein folding is impeded by the complexity of the process. Much of this complexity can be described and understood by taking a statistical approach to the energetics of protein conformation, that is, to ...
J. Bryngelson +3 more
semanticscholar +1 more source
Chemical Synthesis of Microtubule-Associated Protein Tau 2N4R [PDF]
, 2023 Wyatt C. Powell +2 more
openalex +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source