Results 121 to 130 of about 168,206 (155)

Ab initio Tertiary Structure Prediction of Proteins

Journal of Global Optimization, 2003
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Klepeis, J. L., Floudas, C. A.
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Comparison of homologous tertiary structures of proteins

Journal of Theoretical Biology, 1974
Homology in sequences of proteins which have the same or similar function has been studied as a problem of comparative biochemistry and molecular evolution. It is therefore of interest to examine homology in three-dimensional structures, e.g. whether folding of polypeptides having common residues gives rise to the same tertiary structure or not.
K, Nishikawa, T, Ooi
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Computational Methods for Protein Tertiary Structure Analysis

2023
Protein folding accuracy is fundamental to all cells. In spite of this, it is difficult to maintain the fidelity of protein synthesis and folding due to the fact that the implicit genetic and biochemical systems are inherently prone to error, which leads to the constant production of a certain amount of misfolded proteins.
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Protein denaturation and tertiary structure

Journal of Chemical Education, 1986
Students may dutifully learn the concepts of protein structure, but meaning is often abstracted due to the lack of opportunity for observing the physical entity. To bridge this gap, an inexpensive denaturation experiment is designed to demonstrate the presence of tertiary structure.
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The MULTICOM Protein Tertiary Structure Prediction System

2013
With the expansion of genomics and proteomics data aided by the rapid progress of next-generation sequencing technologies, computational prediction of protein three-dimensional structure is an essential part of modern structural genomics initiatives. Prediction of protein structure through understanding of the theories behind protein sequence-structure
Jilong, Li, Debswapna, Bhattacharya, Renzhi, Cao, Badri, Adhikari, Xin, Deng, Jesse, Eickholt, Jianlin, Cheng   +6 more
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Efficient Approaches for Retrieving Protein Tertiary Structures

IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2012
The 3D conformation of a protein in the space is the main factor which determines its function in living organisms. Due to the huge amount of newly discovered proteins, there is a need for fast and accurate computational methods for retrieving protein structures.
Georgina, Mirceva, Ivana, Cingovska, Zoran, Dimov, Danco, Davcev   +3 more
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Does secondary structure determine tertiary structure in proteins?

Proteins: Structure, Function, and Bioinformatics, 2005
AbstractIs highly approximate knowledge of a protein's backbone structure sufficient to successfully identify its family, superfamily, and tertiary fold? To explore this question, backbone dihedral angles were extracted from the known three‐dimensional structure of 2,439 proteins and mapped into 36 labeled, 60° × 60° bins, called mesostates. Using this
Haipeng, Gong, George D, Rose
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Protein Tertiary Structure Prediction

2006
One of the most important scientific achievements of the twentieth century was the discovery of the DNA double helical structure by Watson and Crick in 1953. Strictly speaking, the work was the result of a three-dimensional modeling conducted partly based on data obtained from x-ray diffraction of DNA and partly based on chemical bonding information ...
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Tertiary Structure of Proteins

2010
In Chapter 4, we gave a brief introduction to proteins. The structures of a very large number of proteins have been determined and it is possible to ask fundamental questions: Given the primary sequence, what is tertiary structure? How does the protein fold into the final structure? This “folding problem” has attracted a great deal of attention, and it
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Describing patterns of protein tertiary structure

1985
Publisher Summary This chapter discusses the four major categories of tertiary structure within which subtypes that are more specific described: (1) antiparallel a, (2) parallel α/β, (3) antiparallel β, and (4) small irregular proteins. Within this first major category, the simplest type of structure is the up-and-down helix bundle: an approximate ...
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