Results 131 to 140 of about 166,818 (301)
Prediction and Analysis of Surface Hydrophobic Residues in Tertiary Structure of Proteins [PDF]
, 2014 Shambhu Malleshappa Gowder +3 more
openalex +1 more source
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Structural difficulty index: a reliable measure for modelability of protein tertiary structures [PDF]
, 2016 Rahul Kaushik, B. Jayaram
openalex +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
The pH dependence of hydrogen‐deuterium exchange in trp repressor: The exchange rate of amide protons in proteins reflects tertiary interactions, not only secondary structure [PDF]
, 1996 Michael D. Finucane, Oleg Jardetzky
openalex +1 more source
Bacterial Periplasmic Binding Protein Tertiary Structures
Journal of Biological Chemistry, 1989 M D, Adams, D L, Oxender
openaire +2 more sources
Arthritis Care &Research, EarlyView.Objective Although treat‐to‐target urate‐lowering therapy (ULT) is endorsed as best practice in gout management, limited data exist on its impact on health‐related quality of life (HRQoL). We assessed the impact of treat‐to‐target ULT on HRQoL among participants receiving protocolized gout care, identifying factors associated with HRQoL and HRQoL ...
Austin Barry +16 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla +13 more
wiley +1 more source
Predicting protein tertiary structure and its uncertainty analysis via particle swarm sampling. [PDF]
J Mol Model, 2019 Álvarez Ó +4 more
europepmc +1 more source