Results 11 to 20 of about 168,206 (155)
Tertiary alphabet for the observable protein structural universe [PDF]
Proceedings of the National Academy of Sciences, 2016 Significance Proteins fold into intricate 3D structures, determined by their amino acid sequences. Different proteins can fold into drastically different structures, and the space of all possible structures appears hopelessly complex.
Craig O, Mackenzie +2 more
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Coupled prediction of protein secondary and tertiary structure [PDF]
Proceedings of the National Academy of Sciences, 2003 The strong coupling between secondary and tertiary structure formation in protein folding is neglected in most structure prediction methods. In this work we investigate the extent to which nonlocal interactions in predicted tertiary structures can be used to improve secondary structure prediction.
Jens, Meiler, David, Baker
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Protein–Protein Interactions Mediated by Helical Tertiary Structure Motifs
Journal of the American Chemical Society, 2015 The modulation of protein-protein interactions (PPIs) by means of creating or stabilizing secondary structure conformations is a rapidly growing area of research. Recent success in the inhibition of difficult PPIs by secondary structure mimetics also points to potential limitations, because often, specific cases require tertiary structure mimetics.
Watkins, Andrew M. +2 more
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Frontiers in Microbiology, 2022 Dothistroma septosporum (Ds) and Fulvia fulva (Ff; previously called Cladosporium fulvum) are two closely related Dothideomycete fungal species that cause Dothistroma needle blight in pine and leaf mold in tomato, respectively.
Mariana Tarallo +5 more
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Biomolecules, 2022 With the debut of AlphaFold2, we now can get a highly-accurate view of a reasonable equilibrium tertiary structure of a protein molecule. Yet, a single-structure view is insufficient and does not account for the high structural plasticity of protein ...
Fardina Fathmiul Alam, Amarda Shehu
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Image-based effective feature generation for protein structural class and ligand binding prediction [PDF]
PeerJ Computer Science, 2020 Proteins are the building blocks of all cells in both human and all living creatures of the world. Most of the work in the living organism is performed by proteins.
Nafees Sadique +4 more
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Reducing Ensembles of Protein Tertiary Structures Generated De Novo via Clustering
Molecules, 2020 Controlling the quality of tertiary structures computed for a protein molecule remains a central challenge in de-novo protein structure prediction. The rule of thumb is to generate as many structures as can be afforded, effectively acknowledging that ...
Ahmed Bin Zaman +3 more
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I 3D3P: an Intelligent 3D Protein Prediction Platform
Proceedings of the International Conference on Applied Innovations in IT, 2022 Proteins are macromolecules consisting of a chain of smaller molecules (i.e. amino acids) known as monomers. Three levels of protein structure are distinguished: primary, secondary and tertiary.
Mohamed Hachem Kermani, Zizette Boufaida
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EasyModel: a user-friendly web-based interface based on MODELLER
Scientific Reports, 2023 Three-dimensional protein structures are invaluable sources of information for the functional annotation of protein molecules. Describing the function of a protein sequence is one of the most common problems in biology.
Seyed Shahriar Arab, Alireza Dantism
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Ultrasonics Sonochemistry, 2023 The effects of air thawing (AT), water immersion thawing (WT), microwave thawing (MT) and ultrasound combined with slightly acidic electrolyzed water thawing (UST) on the myofibrillar protein (MP) properties (surface hydrophobicity, solubility, turbidity,
Dewei Kong +8 more
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