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Principal component analysis in protein tertiary structure prediction

Journal of Bioinformatics and Computational Biology, 2018
We discuss applicability of principal component analysis (PCA) for protein tertiary structure prediction from amino acid sequence. The algorithm presented in this paper belongs to the category of protein refinement models and involves establishing a low-dimensional space where the sampling (and optimization) is carried out via particle swarm optimizer (
Óscar, Álvarez   +5 more
openaire   +2 more sources

Effect of methyl substitution on protein tertiary structure

Journal of Theoretical Biology, 1992
Biological effects caused by the post-translational methylation of certain side chains in proteins has been thought to be due solely to changes in charge, steric relations or hydrophobicity at the site of the methyl group. However, there is increasing evidence that the presence of CH3 can also induce a "global" effect on the protein molecule.
W K, Paik, S, Kim
openaire   +2 more sources

CARBOHYDRATE-BINDING PROTEINS: TERTIARY STRUCTURES AND PROTEIN-SUGAR INTERACTIONS

Annual Review of Biochemistry, 1986
PERSPECTIVES AND SUMMARY . 287 TERTIARY STRUCTURES 288 PROTEIN-SUGAR INTERACTIONS 292 Locations of Sugar-Binding Sites in Proteins 294 Hydrogen Bonds and van der Waals Contacts , 300 Oligosaccharide Binding ...
openaire   +2 more sources

Underlying Hydrophobic Sequence Periodicity of Protein Tertiary Structure

Journal of Biomolecular Structure and Dynamics, 2005
Hydropathy plots or window averages over local stretches of the sequence of residue hydrophobicity have revealed patterns related to various protein tertiary structural features. This has enabled identification of regions of the sequence that are at the surface or within the interior of globular soluble proteins, regions located within the lipid ...
openaire   +2 more sources

The contemporary management of cancers of the sinonasal tract in adults

Ca-A Cancer Journal for Clinicians, 2023
Rajat Thawani
exaly  

Highly accurate protein structure prediction with AlphaFold

Nature, 2021
John M Jumper   +2 more
exaly  

The protein corona from nanomedicine to environmental science

Nature Reviews Materials, 2023
Assist Prof Morteza Mahmoudi   +2 more
exaly  

B cells and tertiary lymphoid structures as determinants of tumour immune contexture and clinical outcome

Nature Reviews Clinical Oncology, 2022
Wolf H Fridman   +2 more
exaly  

Protein Denaturation Tertiary Structure

Biochemical Education, 1986
openaire   +1 more source

Treatment of renal cell carcinoma: Current status and future directions

Ca-A Cancer Journal for Clinicians, 2017
Pedro Coelho Barata, Brian I Rini
exaly  

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