Results 41 to 50 of about 168,206 (155)

Predicción computacional de la estructura terciaria de la iduronato 2-sulfato sulfatasa humana

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2007
Introducción. El síndrome de Hunter o mucopolisacaridosis tipo II (MC KUSIK 309900) es causado por la deficiencia de la iduronato 2-sulfato sulfatasa humana (E.C. 3.1.6.13).
Homero Sáenz   +4 more
doaj   +1 more source

IN SILICO CHARACTERIZATION OF HUMAN INTERFERON ALPHA/BETA RECEPTOR 2 (ISOFORM A, B AND C) PROTEIN

open access: yesPakistan Armed Forces Medical Journal, 2021
Objective: To predict the tertiary structure of human interferon alpha/beta receptor 2 protein. Study Design: Structure prediction by using bio informatics tools. Place and Duration of Study: Department of Biochemistry, Swat Medical College (STMC),
Ambreen Javed   +3 more
doaj  

Tertiary Structure of Uracil-DNA Glycosylase Inhibitor Protein [PDF]

open access: yesJournal of Biological Chemistry, 1995
The Bacillus subtilis bacteriophage PBS2 uracil-DNA glycosylase inhibitor (Ugi) is an acidic protein of 84 amino acids that inactivates uracil-DNA glycosylase from diverse organisms. The secondary structure of Ugi consists of five anti-parallel beta-strands and two alpha-helices (Balasubramanian, S., Beger, R.D., Bennett, S.E., Mosbaugh, D.W., and ...
R D, Beger   +4 more
openaire   +2 more sources

In silico characterization and structural modeling of bacterial metalloprotease of family M4

open access: yesJournal of Genetic Engineering and Biotechnology, 2021
Background The M4 family of metalloproteases is comprised of a large number of zinc-containing metalloproteases. A large number of these enzymes are important virulence factors of pathogenic bacteria and therefore potential drug targets.
Rajnee Hasan   +2 more
doaj   +1 more source

PS4: a next-generation dataset for protein single-sequence secondary structure prediction

open access: yesBioTechniques, 2023
Protein secondary structure prediction is a subproblem of protein folding. A light-weight algorithm capable of accurately predicting secondary structure from only the protein residue sequence could provide useful input for tertiary structure prediction ...
Omar Peracha
doaj   +1 more source

Finding protein sites using machine learning methods

open access: yesIngeniería e Investigación, 2003
The increasing amount of protein three-dimensional (3D) structures determined by x-ray and NMR technologies as well as structures predicted by computational methods results in the need for automated methods to provide inital annotations.
Jaime Leonardo Bobadilla Molina   +2 more
doaj  

A triphosphate tunnel metalloenzyme from pear (PbrTTM1) moonlights as an adenylate cyclase

open access: yesFrontiers in Plant Science, 2023
Adenylyl cyclase (AC) is the vital enzyme for generating 3′,5′-cyclic adenosine monophosphate, an important signaling molecule with profound nutritional and medicinal values.
Ye Yuan   +14 more
doaj   +1 more source

The Mrs1 splicing factor binds the bI3 group I intron at each of two tetraloop-receptor motifs. [PDF]

open access: yesPLoS ONE, 2010
Most large ribozymes require protein cofactors in order to function efficiently. The yeast mitochondrial bI3 group I intron requires two proteins for efficient splicing, Mrs1 and the bI3 maturase. Mrs1 has evolved from DNA junction resolvases to function
Caia D S Duncan, Kevin M Weeks
doaj   +1 more source

Analysis of ORF5 protein signifies its importance in Norway rat Hepatitis E virus [PDF]

open access: yesNetwork Biology, 2022
Hepatitis E virus (HEV) is the chief cause of hepatitis E (inflammation of liver) across the globe. The Norway rat HEV genome consists of six open reading frames (ORFs), i.e., ORF1, ORF2, ORF3, ORF4, ORF5 and ORF5.
Zoya Shafat   +2 more
doaj  

A hybrid variational autoencoder and WGAN with gradient penalty for tertiary protein structure generation

open access: yesScientific Reports
Elucidating the tertiary structure of proteins is important for understanding their functions and interactions. While deep neural networks have advanced the prediction of a protein’s native structure from its amino acid sequence, the focus on a single ...
Aalaa I. Sehsah   +2 more
doaj   +1 more source

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