Results 141 to 150 of about 8,268,147 (364)
Retinol-binding protein: the transport protein for vitamin A in human plasma [PDF]
Masamitsu Kanai+2 more
openalex +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi+3 more
wiley +1 more source
Effective Protein-Protein Interaction Exploration with PPIretrieval [PDF]
Protein-protein interactions (PPIs) are crucial in regulating numerous cellular functions, including signal transduction, transportation, and immune defense. As the accuracy of multi-chain protein complex structure prediction improves, the challenge has shifted towards effectively navigating the vast complex universe to identify potential PPIs. Herein,
arxiv
The present study provides the first link between the “classical” machinery regulating protein transport at the Golgi compartment, namely ARF proteins and PKDs, and demonstrates that the direct interaction of both is crucial for efficient protein ...
G. Pusapati+7 more
semanticscholar +1 more source
INTRACELLULAR TRANSPORT OF SECRETORY PROTEINS IN THE PANCREATIC EXOCRINE CELL [PDF]
James D. Jamieson, George E. Palade
openalex +1 more source
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker+14 more
wiley +1 more source
ANKS1A-Deficiency Aberrantly Increases the Entry of the Protein Transport Machinery into the Ependymal Cilia. [PDF]
Lee H, Lee J, Shin M, Park S.
europepmc +1 more source
Persistent Sheaf Laplacian Analysis of Protein Flexibility [PDF]
Protein flexibility, measured by the B-factor or Debye-Waller factor, is essential for protein functions such as structural support, enzyme activity, cellular communication, and molecular transport. Theoretical analysis and prediction of protein flexibility are crucial for protein design, engineering, and drug discovery.
arxiv
Molecular Dynamics Simulation of Folding and Diffusion of Proteins in Nanopores [PDF]
A novel combination of discontinuous molecular dynamics and the Langevin equation, together with an intermediate-resolution model, are used to carry out long (several $\mu$s) simulation and study folding transition and transport of proteins in slit nanopores.
arxiv
The effect of dietary protein deficiency on transport of vitamin A in the blood and its storage in the liver [PDF]
Colin Friend+4 more
openalex +1 more source