Results 211 to 220 of about 79,142 (299)

Receptor protein tyrosine phosphatases control Purkinje neuron firing. [PDF]

Cell Cycle, 2020
Brown AS, Meera P, Quinones G, Magri J, Otis TS, Pulst SM, Oro AE.   +6 more
europepmc   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Phosphoproteomics and morphology of stored human red blood cells treated by protein tyrosine phosphatases inhibitor. [PDF]

Blood Adv
Bardyn M, Crettaz D, Rappaz B, Hamelin R, Armand F, Tissot JD, Turcatti G, Prudent M.   +7 more
europepmc   +1 more source

Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. [PDF]

Int J Mol Sci, 2020
Lai CH, Chang CC, Chuang HC, Tan TH, Lyu PC.   +4 more
europepmc   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Structural and Biochemical Characterization of the Two Drosophila Low Molecular Weight-Protein Tyrosine Phosphatases DARP and Primo-1. [PDF]

Mol Cells, 2020
Lee HS, Mo Y, Shin HC, Kim SJ, Ku B.
europepmc   +1 more source

Dynamic phosphorylation of a small chloroplast protein exhibiting so far undescribed labelling properties [PDF]

, 1991
B Stelte, GD Sabato, H Sze, H Sze, J Soll, J Soll, LE Hokin, R Serrano   +7 more
core   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

Interdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu, Chenning Zhang, Shihan Ma, Zhanxue Xu, Cailing Liang, Fang Cheng, Hongbo Chen   +6 more
wiley   +1 more source

Protocol for CRISPR-Cas12a genome editing of protein tyrosine phosphatases in human pluripotent stem cells and functional β-like cell generation. [PDF]

STAR Protoc
Negueruela J, Vandenbempt V, Talamantes S, Ribeiro-Costa F, Nunes M, Dias A, Bansal M, Gurzov EN.   +7 more
europepmc   +1 more source

In Vitro Activity Assays to Quantitatively Assess the Endogenous Reversible Oxidation State of Protein Tyrosine Phosphatases in Cells. [PDF]

Curr Protoc Chem Biol, 2020
Londhe AD, Londhe AD, Rizvi SHM, Boivin B.   +3 more
europepmc   +1 more source