Results 91 to 100 of about 4,692,035 (317)

Chapter 6: Cereal grain proteins

, 2023
Proteins are essential for the structure, development, and function of the plant cell. They include structural proteins in the membranes of cells and organelles, transporters that move components between and within cells and tissues, enzymes, components ...
Shewry, P. R.
core   +1 more source

Application of docking methodologies to modeled proteins [PDF]

, 2020
Protein docking is essential for structural characterization of protein interactions. Besides providing the structure of protein complexes, modeling of proteins and their complexes is important for understanding the fundamental principles and specific ...
Taras Dauzhenka, Dauzhenka, Taras, Sternberg, Michael JE, Ilya A. Vakser, Amar Singh, Petras J. Kundrotas, Michael J. E. Sternberg, Kundrotas, Petras J, Vakser, Ilya A, Singh, Amar   +9 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Idiosyncratic evolution of conserved eukaryote proteins that are similar in sequence to archaeal or bacterial proteins

, 2008
Sequence comparisons have been made between the proteins of 571 prokaryote species including 46 archaea and 525 bacteria and the set of human proteins.
Roy J. Britten, Britten, Roy J.
core  

Salivary gland proteins of the human malaria vector, Anopheles dirus B (Diptera Culicidae) [PDF]

, 2007
Salivary gland proteins of the human malaria vector, Anopheles dirus B were determined and analyzed. The amount of salivary gland proteins in mosquitoes aged between 3--10 days was approximately 1.08 +/- 0.04 microg/female and 0.1 +/- 0.05 microg/male ...
Mark C. Wilkinson, Bates, Paul A., Thasaneeya Harnnoi, Choochote, Wej, Anuluck Junkum, Wilkinson, Mark, Wilkinson, Mark C, Paul A. Bates, Wej Choochote, Siriyasatein, Padet, Atchariya Jitpakdi, Padet Siriyasatein, Harnnoi, Thasaneeya, Narissara Jariyapan, Jariyapan, Narissara, Bates, Paul A, Junkum, Anuluck, Jitpakdi, Atchariya   +17 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Proteins in biomass streams

, 2010
The focus of this study is to give an overview of traditional and new biomasses and biomass streams that contain proteins. When information was available, the differences in molecular structure and physical and chemical properties for the different ...
Mulder, W.J.
core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Unveiling novel insights into human IL-6 − IL-6R interaction sites through 3D computer-guided docking and systematic site mutagenesis

Scientific Reports
The cytokine interleukin-6 (IL-6) plays a crucial role in autoimmune and inflammatory diseases. Understanding the precise mechanism of IL-6 interaction at the amino acid level is essential to develop IL-6-inhibiting compounds.
Kaitong Li, Junyu Cai, Zhiyang Jiang, Qingbin Meng, Zhao Meng, He Xiao, Guojiang Chen, Chunxia Qiao, Longlong Luo, Jijun Yu, Xinying Li, Yinxiang Wei, Hui Li, Chenghua Liu, Beifen Shen, Jing Wang, Jiannan Feng   +16 more
doaj   +1 more source