Results 121 to 130 of about 5,246,585 (305)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Modulators of Protein–Protein Interactions [PDF]

Chemical Reviews, 2014
Milroy, L., Grossmann, T., Hennig, S., Brunsveld, L., Ottmann, C.   +4 more
openaire   +4 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Spontaneous aging of mature amyloids alters structural stability, cytotoxicity, and susceptibility to biological clearance

Cell Death Discovery
Accumulation of amyloid fibrils is a key factor in the pathogenesis of progressive diseases, including neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease, as well as systemic amyloidosis.
Maksim I. Sulatsky, Olga V. Stepanenko, Arina A. Kayda, Olesya V. Stepanenko, Ekaterina V. Mikhailova, Anna I. Sulatskaya   +5 more
doaj   +1 more source

Identification and characterisation of the Arabidopsis thaliana cell wall proteome: unravelling novel cell wall proteins and new potential functions of the plant extracellular matrix [PDF]

, 2001
The application of the proteomic approach has facilitated efforts directed toward the mapping of the entire Arabidopsis cell wall proteome. Proteins were sequentially extracted from purified cell walls using 0.2 M CaC1(_2) followed by a urea buffer.
Ndimba, Bongani Kaiser
core  

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Rheological Characteristics and Microstructure of Probiotic Soy Yogurt Prepared from Germinated Soybeans

Food Technology and Biotechnology, 2012
Soy yogurts (sogurts) were prepared from germinated soybeans [Glycine max (L.) Merrill] with different hypocotyl lengths. This study is mainly focused on the effects of soybean germination on the rheological characteristics and the microstructure of ...
Mei Yang, Jing Fu, Li Li
doaj  

ATP binding to lysozyme and superfolder GFP amyloid fibrils induces aggregate remodeling and attenuates their cytotoxicity

Cell Death Discovery
The pathogenesis of neurodegenerative diseases such as Alzheimer’s and Parkinson’s, systemic and local amyloidoses is closely associated with amyloid fibril accumulation.
Olga V. Stepanenko, Maksim I. Sulatsky, Kristina G. Gridasova, Ekaterina V. Mikhailova, Anna I. Sulatskaya, Olesya V. Stepanenko   +5 more
doaj   +1 more source

Structural characterization of recombinant humanized type III collagen cold gel and its effects on the biological functions of HaCaT cells

Frontiers in Medicine
Recombinant humanized collagen has been widely used in the biomedical field. This study focuses on the characterization of a novel recombinant humanized type III collagen cold gel (C3Gel).
Yizhe Wang, Sibin Kuang, Yuhui Fan, Danfeng Li, Ling Li, Jian Wang, Wei Bian   +6 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source