Results 151 to 160 of about 10,718,710 (345)

Multiplexed Conformationally Selective, Localized Gas-Phase Hydrogen Deuterium Exchange of Protein Ions Enabled by Transmission-Mode Electron Capture Dissociation

, 2022
Ritu Chaturvedi, Ian Webb
openalex   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Analytical Validation and Clinical Qualification of a New Immunohistochemical Assay for Androgen Receptor Splice Variant-7 Protein Expression in Metastatic Castration-resistant Prostate Cancer

, 2016
Jonathan Welti, Daniel Nava Rodrigues, Adam Sharp, Shihua Sun, David Lorente, Ruth Riisnaes, Ines Figueiredo, Zafeiris Zafeiriou, Pasquale Rescigno, Johann S. de Bono, Stephen R. Plymate   +10 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Protein-protein recognition

Progress in Biophysics and Molecular Biology, 1995
openaire   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Sweelin®, a Novel Sweet Protein, Does Not Affect Blood Glucose and Insulin Levels- a Double-Blind, Randomized, Crossover Clinical Study

Current Developments in Nutrition
Yael Lifshitz, Rotem Saban, Shira Paz, Ilan Samish, Alexandra Jenkins, David Zeltser, Roy Eldor   +6 more
doaj   +1 more source

The molecular activation and regulation mechanisms of proteolytic Toll signaling cascade in insect innate immunity

Invertebrate Survival Journal, 2010
Recently we biochemically determined the molecular recognition and regulatory mechanisms of how beetle’s larvae recognize Gram-positive bacteria and fungi via Toll signaling cascade.
K H Ryu, J W Park, K Kurokawa, M Matsushita, B L Lee   +4 more
doaj  

Roles of RcsA, an AhpD Family Protein, in Reactive Chlorine Stress Resistance and Virulence in Pseudomonas aeruginosa

, 2020
Benya Nontaleerak, Jintana Duang-nkern, Lampet Wongsaroj, Wachareeporn Trinachartvanit, Adisak Romsang, Skorn Mongkolsuk   +5 more
openalex   +2 more sources

Organic chemical approach to photo-crosslinks of nucleic acids to proteins [PDF]

, 1980
Teruo Matsuura, Isao Saito, Satoru Ito, H. Sugiyama, Tetsuya Shinmura   +4 more
openalex   +1 more source