Results 161 to 170 of about 10,300,849 (340)
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa+13 more
wiley +1 more source
Comparison of the Erythrocyte Sedimentation Rate, C-Reactive Protein, Serum Diphenylamine, and Tetrammonium Tests in Rheumatic Fever and Rheumatic Heart Disease [PDF]
R. D. Eastham, P. Székely, Kade Davison
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Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu+7 more
wiley +1 more source
The non-protein nitrogen of extracts of Pisum sativum [PDF]
Sheenah K. Bisset
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KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock+10 more
wiley +1 more source
The chemistry of connective tissues. 3. Composition of the soluble proteins derived from elastin [PDF]
S. M. Partridge, H. F. Davis
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CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar+4 more
wiley +1 more source
BINDING OF CORTICOSTEROIDS BY PLASMA PROTEINS. III. THE BINDING OF CORTICOSTEROID AND RELATED HORMONES BY HUMAN PLASMA AND PLASMA PROTEIN FRACTIONS AS MEASURED BY EQUILIBRIUM DIALYSIS12 [PDF]
William H. Daughaday
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