Results 201 to 210 of about 3,501,692 (266)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Dynamic disorder is crucial for mitochondrial protein import. [PDF]

open access: yesProtein Sci
Schneider J   +3 more
europepmc   +1 more source

Genome Wide Identification and Characterization of <i>BrE2F</i> Family Gene of <i>Brassica rapa</i>. [PDF]

open access: yesInt J Genomics
Sultana N   +7 more
europepmc   +1 more source

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