Results 221 to 230 of about 3,501,692 (266)

The impact of protein flexibility on protein–protein docking

Proteins: Structure, Function, and Bioinformatics, 2004
AbstractAccounting for protein flexibility in protein–protein docking algorithms is challenging, and most algorithms therefore treat proteins as rigid bodies or permit side‐chain motion only. While the consequences are obvious when there are large conformational changes upon binding, the situation is less clear for the modest conformational changes ...
Lutz P, Ehrlich, Michael, Nilges, Rebecca C, Wade   +2 more
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Protein-Protein Interactions

1954
Publisher Summary This chapter focuses on protein–protein interaction. The unique characteristics of different proteins are developed in the interactions of proteins with each other, with ions, and with nonprotein materials such as lipids, nucleic acids, and carbohydrates.
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Protein modules and protein-protein interaction. Introduction.

Advances in protein chemistry, 2002
info:eu-repo/semantics ...
Janin, Joël, Wodak, Shoshana
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Correlating Protein–DNA and Protein–Protein Interaction Networks

Journal of Molecular Biology, 2003
Here, we search protein-DNA binding data for prevalent pairs and higher-order tuples of co-occurring transcription factors (TF) in Saccharomyces cerevisiae. While the identification of such modules is dependent on uncertainties of genome-wide data sets, we find several biologically meaningful examples, which allow putative annotation of yet ...
Manke, T., Bringas, R., Vingron, M.
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Challenges of Protein-Protein Docking of the Membrane Proteins

Despite the recent advances in the determination of high-resolution membrane protein (MP) structures, the structural and functional characterization of MPs remains extremely challenging, mainly due to the hydrophobic nature, low abundance, poor expression, purification, and crystallization difficulties associated with MPs.
Yusra Sajid, Kiani, Ishrat, Jabeen
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Proteine, Proteine

forschung, 2018
AbstractSonja Lorenz erforscht das in allen Körperzellen wirksame Ubiquitinsystem.
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Protein recruitment systems for the analysis of protein–protein interactions

Biochemical Pharmacology, 2000
The yeast Saccharomyces cerevisiae serves as an excellent genetic tool for the analysis of protein +/- protein interactions. The most common system, used to date, is the two-hybrid system. Although proven very powerful, the two-hybrid system exhibits several inherent problems and limitations.
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Protein Arrays: Labeling the Protein and Probing the Array for Protein-Protein Interactions

Cold Spring Harbor Protocols, 2007
INTRODUCTIONTo detect protein-protein interactions, a protein microarray can be incubated with a fluorescently labeled protein. After the array is washed, stable interactions can be identified by scanning the slide for fluorescent spots. This protocol uses cyanine-3 (Cy3) or cyanine-5 (Cy5) monofunctionally activated dyes to label the probe proteins.
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Protein Phosphorylation and Protein-Protein Interactions

2002
Intracellular signaling is the series of events which translates the specific message of circulating ligands into a particular biological response in target cells. The first step in hormone signaling involves the interaction between a ligand and its cognate receptor (membrane or nuclear), which in turn induces stoichiometric and conformational changes ...
Vincent Goffin, Paul A. Kelly
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Protein-Protein Interactions

2004
Pedrazzi G, Stagljar I
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