Results 221 to 230 of about 4,998,947 (297)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Serum proteins associated with LDL-C and non-HDL-C reduction in response to dietary interventions in the DASH and DASH-Sodium trials.

Food Funct
Kim H, Lichtenstein AH, Coresh J, Appel LJ, Rebholz CM.   +4 more
europepmc   +1 more source

Mass spectrometry-based peripheral blood proteomics for biomarker discovery in idiopathic pulmonary fibrosis. [PDF]

Respir Res
Menon AA, Gansen B, Mulder H, Neely ML, Papavasileiou P, Salisbury ML, Southern BD, Hesslinger C, Leonard TB, Meissner F, Todd JL.   +10 more
europepmc   +1 more source

SULFUR IN PROTEINS

, 1927
Ross Aiken Gortner, Walter F. Hoffman
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Proteome-wide and network pharmacology integration identifies sunitinib as a potential therapeutic for type 2 diabetes targets. [PDF]

Ther Adv Endocrinol Metab
Kong Y, Zhu HW, Tong HX, Shi L, Yu H.
europepmc   +1 more source

THE FATE OF PROTEIN DIGESTION PRODUCTS IN THE BODY

, 1913
Donald D. Van Slyke, G.M. Meyer
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Protein fingerprints of brain-derived extracellular vesicles predict types of tau pathology. [PDF]

Alzheimers Res Ther
Espourteille J, Barve A, Zufferey V, Leroux E, Perbet R, Bégard S, Caillierez R, Maurage CA, Toni N, Buée L, Colin M, Richetin K.   +11 more
europepmc   +1 more source

MAINTENANCE EXPERIMENTS WITH ISOLATED PROTEINS

, 1912
Thomas B. Osborne, Lafayette B. Mendel, L.Ferry Edna   +2 more
openalex   +1 more source