Results 221 to 230 of about 10,718,710 (345)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Potential new biomarkers in pig saliva for differentiating between the effects of different conditions of mixing and density at pre-slaughter: A preliminary proteomicstudy. [PDF]

Anim Welf
Botía M, Muñoz-Prieto A, Ortín Bustillo A, Rešetar-Maslov D, Rubić I, Fuentes P, Jiménez-Caparrós FJ, Hernández-Gómez JL, Avellaneda A, Ceron JJ, Tecles F, Mrljak V, Escribano D.   +12 more
europepmc   +1 more source

Chromatographic and Electrophoretic Fractionation of Soluble Proteins of Brain and Liver

, 1965
Blake W. Moore, Douglas McGregor
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Integrating evidence from protein domains to identify cancer driver mutations. [PDF]

Protein Sci
Ostroverkhova D, Sheng Y, Rogozin I, Panchenko AR.   +3 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Five differentially expressed proteins identified to serve as potential blood biomarkers for schizophrenia screening based on proteomics. [PDF]

Front Psychiatry
Li R, Fu X, Li C, Yuan L, Liu Y, Yang L, Fang X, Zhang X, Zhang G, Du X.   +9 more
europepmc   +1 more source

Proteasome Inhibitors Cause Induction of Heat Shock Proteins and Trehalose, Which Together Confer Thermotolerance in Saccharomyces cerevisiae

, 1998
Do Hee Lee, Alfred L. Goldberg
openalex   +2 more sources

Abscisic Acid Inhibits Type 2C Protein Phosphatases via the PYR/PYL Family of START Proteins

Science, 2009
Sang-Youl Park, Pauline Fung, N. Nishimura, Davin R. Jensen, Hiroaki Fujii, Yang Zhao, Shelley Lumba, J. Santiago, Américo Rodrigues, T. F. Chow, S. Alfred, D. Bonetta, R. Finkelstein, N. Provart, D. Desveaux, P. L. Rodriguez, P. McCourt, Jian‐Kang Zhu, J. Schroeder, B. Volkman, S. Cutler   +20 more
semanticscholar   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source