Results 31 to 40 of about 13,339,631 (403)
INTRINSIC PROTEIN DISORDER AND PROTEIN-PROTEIN INTERACTIONS [PDF]
Biocomputing 2012, 2011 Intrinsically disordered proteins often bind to more than one partner. In this study, we focused on 11 sets of complexes in which the same disordered segment becomes bound to two or more distinct partners. For this collection of protein complexes, two or more partners of each disordered segment were selected to have less than 25% amino acid identity ...
Bin Xue +7 more
openaire +4 more sources
Scientific Reports, 2021 Increasing evidence has indicated that adult neurogenesis contributes to brain plasticity, although function of new neurons is still under debate. In opossums, we performed an olfactory-guided behavior task and examined the association between olfactory ...
Beata Tepper +5 more
doaj +1 more source
Untying Knots in Proteins [PDF]
, 2010 A shoelace can be readily untied by pulling its ends rather than its loops. Attempting to untie a native knot in a protein can also succeed or fail depending on where one pulls.
Cieplak, Marek +3 more
core +2 more sources
Food proteins and peptides [PDF]
, 2015 The qualitative and quantitative determination of proteins and peptides in raw or processed food is experiencing a growing interest and importance from both scientific and economic point of view.
CAPRIOTTI, ANNA LAURA +5 more
core +1 more source
Protein–Protein and Protein–Membrane Associations in the Lignin Pathway [PDF]
The Plant Cell, 2012 Supramolecular organization of enzymes is proposed to orchestrate metabolic complexity and help channel intermediates in different pathways. Phenylpropanoid metabolism has to direct up to 30% of the carbon fixed by plants to the biosynthesis of lignin precursors. Effective coupling of the enzymes in the pathway thus seems to be required.
Bassard, Jean-Etienne +13 more
openaire +5 more sources
Heat shock proteins in health and disease: therapeutic targets or therapeutic agents? [PDF]
, 2001 For many years, heat shock or stress proteins have been regarded as intracellular molecules that have a range of housekeeping and cytoprotective functions, only being released into the extracellular environment in pathological situations such as necrotic
Pockley, A.G.
core +1 more source
Morphology of protein–protein interfaces [PDF]
Structure, 1998 Most soluble proteins are active as low-number oligomers. Statistical surveys of oligomeric proteins have defined the roles of hydrophobicity and complementarity in the stability of protein interfaces, but tend to average structural features over a diverse set of protein-protein interfaces, blurring information on how individual interfaces are ...
David S. Goodsell +2 more
openaire +3 more sources
Haematologica, 2016 It has been proposed that von Willebrand factor might affect factor VIII immunogenicity by reducing factor VIII uptake by antigen presenting cells. Here we investigate the interaction of recombinant von Willebrand factor with immature monocyte-derived ...
Nicoletta Sorvillo +8 more
doaj +1 more source
ESC Heart Failure, 2020 Aims Cardiac transthyretin amyloidosis (ATTR‐CM) is a progressive and fatal condition. Prognosis can be determined at diagnosis according to the National Amyloidosis Centre (NAC) transthyretin amyloidosis (ATTR) stage.
Steven Law +14 more
doaj +1 more source
14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains
Communications Biology, 2021 Pohl et al. investigated the structural basis of Nedd4-2 regulation by 14-3-3 and found that phosphorylated Ser342 and Ser448 are the main residues that facilitate 14-3-3 binding to Nedd4-2.
Pavel Pohl +4 more
doaj +1 more source